Anti-CTNNBIP1 Antibody (CAB0914)
- SKU:
- CAB0914
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CTNNBIP1
- ICAT
- beta-catenin-interacting protein 1
Description
Product Name: | CTNNBIP1 Rabbit mAb |
Product Code: | CAB0914 |
Size: | 20uL, 50uL, 100uL |
Synonyms: | CTNNBIP1, ICAT, beta-catenin-interacting protein 1 |
Applications: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human CTNNBIP1. |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | TE-1 |
Immunogen: | A synthesized peptide derived from human CTNNBIP1. |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 56998 |
Uniprot: | Q9NSA3 |
Cellular Location: | Cytoplasm, Nucleus |
Calculated MW: | 12kDa |
Observed MW: | 11KDa |
UniProt Protein Function: | CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Inhibitor Chromosomal Location of Human Ortholog: 1p36.22 Cellular Component: nucleoplasm; cytoplasm; nucleus; beta-catenin destruction complex; cytosol Molecular Function:protein binding; beta-catenin binding Biological Process: anterior/posterior pattern formation; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud branching; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of protein binding; regulation of vascular permeability during acute inflammatory response; negative regulation of DNA binding |
NCBI Summary: | The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NSA3 |
NCBI GenInfo Identifier: | 59889555 |
NCBI Gene ID: | 56998 |
NCBI Accession: | NP_001012329.1 |
UniProt Secondary Accession: | Q9NSA3,Q9JJN6, |
UniProt Related Accession: | Q9NSA3 |
Molecular Weight: | 9,170 Da |
NCBI Full Name: | beta-catenin-interacting protein 1 |
NCBI Synonym Full Names: | catenin, beta interacting protein 1 |
NCBI Official Symbol: | CTNNBIP1 |
NCBI Official Synonym Symbols: | ICAT |
NCBI Protein Information: | beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; inhibitor of beta-catenin and Tcf-4 |
UniProt Protein Name: | Beta-catenin-interacting protein 1 |
UniProt Synonym Protein Names: | Inhibitor of beta-catenin and Tcf-4 |
UniProt Gene Name: | CTNNBIP1 |
UniProt Entry Name: | CNBP1_HUMAN |