Anti-CREBBP Antibody (CAB17096)
- SKU:
- CAB17096
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CREBBP Antibody |
| Antibody SKU: | CAB17096 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of mouse CREBBP. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse brain, Rat brain |
| Immunogen: | Recombinant protein of mouse CREBBP. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 12914 |
| Uniprot: | Q6GQV9 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 172kDa |
| Observed MW: | 290kDa |
 | Western blot - CREBBP Rabbit pAb (CAB17096) |
| Synonyms: | CREBBP, CBP, KAT3A, RSTS, RSTS1 |
| Background: | This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Code: | Q6GQV9 |
| NCBI GenInfo Identifier: | 81884771 |
| NCBI Gene ID: | 12914 |
| NCBI Accession: | |
| UniProt Related Accession: | P45481 |
| Molecular Weight: | 172kDa |
| NCBI Full Name: | Crebbp protein |
| NCBI Synonym Full Names: | CREB binding protein |
| NCBI Official Symbol: | Crebbp |
| NCBI Official Synonym Symbols: | CBP; KAT3A; AW558298; CBP/p300; p300/CBP |
| NCBI Protein Information: | CREB-binding protein |
| UniProt Protein Name: | |
| Protein Family: | CREB-binding protein |
| UniProt Gene Name: |
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