Anti-CRCP Antibody (CAB4657)
- SKU:
- CAB4657
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CRCP
- CGRP-RCP
- CGRPRCP
- RCP
- RCP9
Frequently bought together:
Description
| Product Name: | CRCP Rabbit pAb |
| Product Code: | CAB4657 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CRCP, CGRP-RCP, CGRPRCP, RCP, RCP9 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human CRCP (NP_001035737.1). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, HeLa, Jurkat, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human CRCP (NP_001035737.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEVK DANS ALLS NYET LKYI SKTP CRHQ SPEI VREF LTAL KSHK LTKA EKLQ LLNH RPVT AVEI QLMV EESE ERLT EEQI EALL HTVT SILP AEPE AEQK KNTN SNVA MDEE DPA |
| Gene ID: | 27297 |
| Uniprot: | O75575 |
| Cellular Location: | Cell membrane, Cytoplasmic side, Nucleus, Peripheral membrane protein |
| Calculated MW: | 8kDa/13kDa/15kDa/16kDa |
| Observed MW: | 20kDa |
| UniProt Protein Function: | CGRP-RCP: an ubiquitous coupling protein for the calcitonin gene-related peptide (CGRP) and adrenomedullin receptors. Modulates ligand responsiveness in a variety of tissues. Two splice-variant isoforms have been described. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 7q11.21 Cellular Component: nucleoplasm; DNA-directed RNA polymerase III complex; plasma membrane; acrosome; cytosol Molecular Function:calcitonin gene-related polypeptide receptor activity; DNA-directed RNA polymerase activity; nucleotide binding Biological Process: transcription from RNA polymerase III promoter; transcription initiation from RNA polymerase III promoter; termination of RNA polymerase III transcription; neuropeptide signaling pathway; positive regulation of interferon type I production; innate immune response; gene expression; defense response to virus; RNA elongation from RNA polymerase III promoter |
| NCBI Summary: | This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75575 |
| NCBI GenInfo Identifier: | 20532033 |
| NCBI Gene ID: | 27297 |
| NCBI Accession: | O75575.1 |
| UniProt Secondary Accession: | O75575,Q3KRA3, Q5HYF1, Q8IXL4, A8MUZ4, A8MW23, B2R4H4 B4E198, |
| UniProt Related Accession: | O75575 |
| Molecular Weight: | 148 |
| NCBI Full Name: | DNA-directed RNA polymerase III subunit RPC9 |
| NCBI Synonym Full Names: | CGRP receptor component |
| NCBI Official Symbol: | CRCP |
| NCBI Official Synonym Symbols: | RCP; RCP9; CGRPRCP; CGRP-RCP |
| NCBI Protein Information: | DNA-directed RNA polymerase III subunit RPC9; RNA polymerase III subunit C9; CGRP-receptor component protein; calcitonin gene-related peptide-receptor component protein |
| UniProt Protein Name: | DNA-directed RNA polymerase III subunit RPC9 |
| UniProt Synonym Protein Names: | Calcitonin gene-related peptide-receptor component protein; CGRP-RCP; CGRP-receptor component protein; CGRPRCP; HsC17 |
| Protein Family: | DNA-directed RNA polymerase |
| UniProt Gene Name: | CRCP |
| UniProt Entry Name: | RPC9_HUMAN |
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