Anti-Cpn10 Antibody (CAB5580)
- SKU:
- CAB5580
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Antibody Name: | Anti-Cpn10 Antibody |
Antibody SKU: | CAB5580 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human Cpn10 |
Application: | WB IHC IF |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | MCF7, C6, U-251MG, Neuro-2a, Rat kidney |
Immunogen: | A synthesized peptide derived from human Cpn10 |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 3336 |
Uniprot: | P61604 |
Cellular Location: | |
Calculated MW: | 11kDa |
Observed MW: | 11KDa |
Synonyms: | CPN10, EPF, GROES, HSP10 |
Background: | This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011] |
UniProt Protein Function: | HSPE1: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. Belongs to the GroES chaperonin family. |
UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 2q33.1 Cellular Component: membrane; mitochondrial matrix; mitochondrion Molecular Function:ATP binding; chaperone binding; protein binding; unfolded protein binding Biological Process: caspase activation; osteoblast differentiation; protein folding; response to unfolded protein |
NCBI Summary: | This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011] |
UniProt Code: | P61604 |
NCBI GenInfo Identifier: | 47606335 |
NCBI Gene ID: | 3336 |
NCBI Accession: | P61604.2 |
UniProt Secondary Accession: | P61604,O95421, Q04984, Q53X54, Q9UDH0, |
UniProt Related Accession: | P61604 |
Molecular Weight: | 10,932 Da |
NCBI Full Name: | 10 kDa heat shock protein, mitochondrial |
NCBI Synonym Full Names: | heat shock protein family E (Hsp10) member 1 |
NCBI Official Symbol: | HSPE1 |
NCBI Official Synonym Symbols: | EPF; CPN10; GROES; HSP10 |
NCBI Protein Information: | 10 kDa heat shock protein, mitochondrial |
UniProt Protein Name: | 10 kDa heat shock protein, mitochondrial |
UniProt Synonym Protein Names: | 10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF |
UniProt Gene Name: | HSPE1 |
UniProt Entry Name: | CH10_HUMAN |