Anti-CPA1 Antibody (CAB3803)
- SKU:
- CAB3803
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CPA1 Antibody |
| Antibody SKU: | CAB3803 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-419 of human CPA1 (NP_001859.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-419 of human CPA1 (NP_001859.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ARST DTFN YATY HTLE EIYD FLDL LVAE NPHL VSKI QIGN TYEG RPIY VLKF STGG SKRP AIWI DTGI HSRE WVTQ ASGV WFAK KITQ DYGQ DAAF TAIL DTLD IFLE IVTN PDGF AFTH STNR MWRK TRSH TAGS LCIG VDPN RNWD AGFG LSGA SSNP CSET YHGK FANS EVEV KSIV DFVK DHGN IKAF ISIH SYSQ LLMY PYGY KTEP VPDQ DELD QLSK AAVT ALAS LYGT KFNY GSII KAIY QASG STID WTYS QGIK YSFT FELR DTGR YGFL LPAS QIIP TAKE TWLA LLTI MEHT LNHP Y |
| Gene ID: | 1357 |
| Uniprot: | P15085 |
| Cellular Location: | Secreted |
| Calculated MW: | 47kDa |
| Observed MW: | Refer to figures |
| Synonyms: | CPA1, CPA |
| Background: | This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. |
| UniProt Protein Function: | CPA1: Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Belongs to the peptidase M14 family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Protease; EC 3.4.17.1; Secreted Chromosomal Location of Human Ortholog: 7q32 Cellular Component: extracellular space Molecular Function:zinc ion binding; metallocarboxypeptidase activity Biological Process: proteolysis |
| NCBI Summary: | Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a monomeric pancreatic exopeptidase involved in zymogen inhibition. [provided by RefSeq, Jan 2009] |
| UniProt Code: | P15085 |
| NCBI GenInfo Identifier: | 399196 |
| NCBI Gene ID: | 1357 |
| NCBI Accession: | P15085.2 |
| UniProt Secondary Accession: | P15085,Q53XU0, Q9BS67, Q9UCF2, A4D1M1, |
| UniProt Related Accession: | P15085 |
| Molecular Weight: | 419 |
| NCBI Full Name: | Carboxypeptidase A1 |
| NCBI Synonym Full Names: | carboxypeptidase A1 (pancreatic) |
| NCBI Official Symbol: | CPA1 |
| NCBI Official Synonym Symbols: | CPA |
| NCBI Protein Information: | carboxypeptidase A1; pancreatic carboxypeptidase A |
| UniProt Protein Name: | Carboxypeptidase A1 |
| Protein Family: | Carboxypeptidase |
| UniProt Gene Name: | CPA1 |
| UniProt Entry Name: | CBPA1_HUMAN |
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