Anti-COLEC12 Antibody (CAB10422)

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SKU:
CAB10422
Product type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Frequently bought together:

Description

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Antibody Name:Anti-COLEC12 Antibody
Antibody SKU:CAB10422
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human COLEC12 (NP_569057.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:A-549, U-87MG, 293T, Mouse lung, Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human COLEC12 (NP_569057.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KVVE KMDN VTGG METS RQTY DDKL TAVE SDLK KLGD QTGK KAIS TNSE LSTF RSDI LDLR QQLR EITE KTSK NKDT LEKL QASG DALV DRQS QLKE TLEN NSFL ITTV NKTL QAYN GYVT NLQQ DTSV LQGN LQNQ MYSH NVVI MNLN NLNL TQVQ QRNL ITNL QRSV DDTS QAIQ RIKN DFQN LQQV FLQA KKDT DWLK EKVQ SLQT LAA
Gene ID:81035
Uniprot:Q5KU26
Cellular Location:Membrane, Single-pass type II membrane protein
Calculated MW:81kDa
Observed MW:110kDa
Synonyms:COLEC12, CLP1, NSR2, SCARA4, SRCL
Background:This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
NCBI Summary:This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells. [provided by RefSeq, Oct 2011]
UniProt Code:Q5KU26
NCBI GenInfo Identifier:18641360
NCBI Gene ID:81035
NCBI Accession:NP_569057.1
UniProt Secondary Accession:Q5KU26,Q6P9F2, Q8TCR2, Q8WZA4, Q9BY85, Q9BYH7,
UniProt Related Accession:Q5KU26
Molecular Weight:81,515 Da
NCBI Full Name:collectin-12
NCBI Synonym Full Names:collectin sub-family member 12
NCBI Official Symbol:COLEC12  
NCBI Official Synonym Symbols:CLP1; NSR2; SRCL; SCARA4  
NCBI Protein Information:collectin-12; hCL-P1; collectin placenta protein 1; nurse cell scavenger receptor 2; scavenger receptor class A, member 4; scavenger receptor with C-type lectin
UniProt Protein Name:Collectin-12
UniProt Synonym Protein Names:Collectin placenta protein 1; CL-P1; hCL-P1; Nurse cell scavenger receptor 2; Scavenger receptor class A member 4; Scavenger receptor with C-type lectin
Protein Family:Zinc finger protein CONSTANS
UniProt Gene Name:COLEC12  
UniProt Entry Name:COL12_HUMAN
Anti-COLEC12 Antibody (CAB10422)Western blot analysis of extracts of various cell lines, using COLEC12 antibody (CAB10422) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.

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