Anti-CNPY2 Antibody (CAB12197)
- SKU:
- CAB12197
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CNPY2 Antibody |
| Antibody SKU: | CAB12197 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of human CNPY2 (NP_055070.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, SGC-7901, HeLa, HepG2, Mouse liver, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of human CNPY2 (NP_055070.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKGW GWLA LLLG ALLG TAWA RRSQ DLHC GACR ALVD ELEW EIAQ VDPK KTIQ MGSF RINP DGSQ SVVE VPYA RSEA HLTE LLEE ICDR MKEY GEQI DPST HRKN YVRV VGRN GESS ELDL QGIR IDSD ISGT LKFA CESI VEEY EDEL IEFF SREA DNVK DKLC SKRT DLCD HALH ISHD EL |
| Gene ID: | 10330 |
| Uniprot: | Q9Y2B0 |
| Cellular Location: | Endoplasmic reticulum |
| Calculated MW: | 9kDa/20kDa |
| Observed MW: | 21kDa |
| Synonyms: | CNPY2, HP10390, MSAP, TMEM4, ZSIG9 |
| Background: |
| UniProt Protein Function: | TMEM4: Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum; Membrane protein, integral; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 12q13.3 Cellular Component: endoplasmic reticulum; integral to plasma membrane Molecular Function:protein binding Biological Process: enzyme linked receptor protein signaling pathway; positive regulation of low-density lipoprotein receptor biosynthetic process; tissue development |
| UniProt Code: | Q9Y2B0 |
| NCBI GenInfo Identifier: | 50401205 |
| NCBI Gene ID: | 10330 |
| NCBI Accession: | Q9Y2B0.1 |
| UniProt Secondary Accession: | Q9Y2B0,Q9UHE9, B2R7B9, |
| UniProt Related Accession: | Q9Y2B0 |
| Molecular Weight: | 21kDa |
| NCBI Full Name: | Protein canopy homolog 2 |
| NCBI Synonym Full Names: | canopy FGF signaling regulator 2 |
| NCBI Official Symbol: | CNPY2 |
| NCBI Official Synonym Symbols: | MSAP; TMEM4; ZSIG9; HP10390 |
| NCBI Protein Information: | protein canopy homolog 2 |
| UniProt Protein Name: | Protein canopy homolog 2 |
| UniProt Synonym Protein Names: | MIR-interacting saposin-like protein; Putative secreted protein Zsig9; Transmembrane protein 4 |
| Protein Family: | Protein canopy |
| UniProt Gene Name: | CNPY2 |
 | Western blot analysis of extracts of various cell lines, using CNPY2 antibody (CAB12197) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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