Anti-CNDP2 Antibody (CAB10381)
- SKU:
- CAB10381
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CNDP2 Antibody |
| Antibody SKU: | CAB10381 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human CNDP2 (NP_060705.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | NCI-H460, LO2, Mouse kidney, Mouse liver, Mouse lung, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human CNDP2 (NP_060705.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAL TTLF KYID ENQD RYIK KLAK WVAI QSVS AWPE KRGE IRRM MEVA AADV KQLG GSVE LVDI GKQK LPDG SEIP LPPI LLGR LGSD PQKK TVCI YGHL DVQP AALE DGWD SEPF TLVE RDGK LYGR GSTD DKGP VAGW INAL EAYQ KTGQ EIPV NVRF CLEG MEES GSEG LDEL IFAR KDTF FKDV DYVC ISDN YWLG KKKP CITY GL |
| Gene ID: | 55748 |
| Uniprot: | Q96KP4 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 43kDa/52kDa |
| Observed MW: | 53kDa |
| Synonyms: | CNDP2, CN2, CPGL, HEL-S-13, HsT2298, PEPA |
| Background: |
| UniProt Protein Function: | CNDP2: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Belongs to the peptidase M20A family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.13.18; Protease Chromosomal Location of Human Ortholog: 18q22.3 Cellular Component: cytosol; nucleoplasm Molecular Function:carboxypeptidase activity Biological Process: glutathione biosynthetic process; sulfur amino acid metabolic process |
| NCBI Summary: | CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96KP4 |
| NCBI GenInfo Identifier: | 23396498 |
| NCBI Gene ID: | 55748 |
| NCBI Accession: | Q96KP4.2 |
| UniProt Secondary Accession: | Q96KP4,Q8WY59, Q9BQ94, Q9NVB4, B3KUG4, V9HWE5, |
| UniProt Related Accession: | Q96KP4 |
| Molecular Weight: | 53kDa |
| NCBI Full Name: | Cytosolic non-specific dipeptidase |
| NCBI Synonym Full Names: | carnosine dipeptidase 2 |
| NCBI Official Symbol: | CNDP2 |
| NCBI Official Synonym Symbols: | CN2; CPGL; PEPA; HsT2298; HEL-S-13 |
| NCBI Protein Information: | cytosolic non-specific dipeptidase |
| UniProt Protein Name: | Cytosolic non-specific dipeptidase |
| UniProt Synonym Protein Names: | CNDP dipeptidase 2; Carnosine dipeptidase II |
| Protein Family: | Cytosolic non-specific dipeptidase |
| UniProt Gene Name: | CNDP2 |
 | Western blot analysis of extracts of various cell lines, using CNDP2 antibody (CAB10381) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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