Anti-Clathrin heavy chain Antibody (CAB4943)
- SKU:
- CAB4943
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CHC
- CHC17
- CLH-17
- CLTCL2
- Hc
Description
| Product Name: | Clathrin heavy chain Rabbit mAb |
| Product Code: | CAB4943 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CHC, CHC17, CLH-17, CLTCL2, Hc |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Clathrin heavy chain |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | NIH/3T3, Jurkat, C6, Mouse kidney, Rat kidney |
| Immunogen: | A synthesized peptide derived from human Clathrin heavy chain |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1213 |
| Uniprot: | Q00610/P53675 |
| Cellular Location: | Cytoplasmic side, Cytoplasmic vesicle membrane, Melanosome, Membrane, Peripheral membrane protein, coated pit |
| Calculated MW: | 191kDa |
| Observed MW: | 192KDa |
| UniProt Protein Function: | CLTC: a major protein component of the cytoplasmic face of coated vesicles and coated pits. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Vesicle Chromosomal Location of Human Ortholog: 17q23.1 Cellular Component: clathrin coat; clathrin-coated vesicle; cytosol; endosome; extracellular matrix; focal adhesion; lysosome; membrane; plasma membrane; protein complex; spindle; trans-Golgi network membrane Molecular Function:clathrin light chain binding; double-stranded RNA binding; protein binding; protein kinase binding; RNA binding Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; clathrin cage assembly; microtubule-based movement; mitotic cell cycle; osteoblast differentiation; receptor internalization; receptor-mediated endocytosis; retrograde transport, endosome to Golgi; transferrin transport; Wnt receptor signaling pathway, planar cell polarity pathway |
| NCBI Summary: | Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q00610 |
| NCBI GenInfo Identifier: | 1705916 |
| NCBI Gene ID: | 1213 |
| NCBI Accession: | Q00610.5 |
| UniProt Secondary Accession: | Q00610,Q6N0A0, Q86TF2, D3DU00, |
| UniProt Related Accession: | Q00610 |
| Molecular Weight: | 192kDa |
| NCBI Full Name: | Clathrin heavy chain 1 |
| NCBI Synonym Full Names: | clathrin heavy chain |
| NCBI Official Symbol: | CLTC |
| NCBI Official Synonym Symbols: | Hc; CHC; CHC17; CLH-17; CLTCL2 |
| NCBI Protein Information: | clathrin heavy chain 1 |
| UniProt Protein Name: | Clathrin heavy chain 1 |
| UniProt Synonym Protein Names: | Clathrin heavy chain on chromosome 17; CLH-17 |
| Protein Family: | Clathrin |
| UniProt Gene Name: | CLTC |
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