Anti-CHORDC1 Antibody (CAB17135)
- SKU:
- CAB17135
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-CHORDC1 Antibody |
| Antibody SKU: | CAB17135 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TKGR HNSE KPPE PVKP EVKT TEKK ELCE LKPK FQEH IIQA PKPV EAIK RPSP DEPM TNLE LKIS ASLK QALD KLKL SSGN EENK KEED NDEI KIGT SCKN G |
| Gene ID: | 26973 |
| Uniprot: | Q9UHD1 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | CHORDC1, CHP1 |
| Background: |
| UniProt Protein Function: | CHORDC1: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Calcium-binding Chromosomal Location of Human Ortholog: 11q14.3 Molecular Function:protein binding; zinc ion binding; Hsp90 protein binding |
| UniProt Code: | Q9UHD1 |
| NCBI GenInfo Identifier: | 221316570 |
| NCBI Gene ID: | 26973 |
| NCBI Accession: | NP_001137545.1 |
| UniProt Secondary Accession: | Q9UHD1,Q6IN49, Q8WVL9, Q9H3D6, B2R6P8, |
| UniProt Related Accession: | Q9UHD1 |
| Molecular Weight: | 37490 |
| NCBI Full Name: | cysteine and histidine-rich domain-containing protein 1 isoform b |
| NCBI Synonym Full Names: | cysteine and histidine-rich domain (CHORD) containing 1 |
| NCBI Official Symbol: | CHORDC1 |
| NCBI Official Synonym Symbols: | CHP1 |
| NCBI Protein Information: | cysteine and histidine-rich domain-containing protein 1 |
| UniProt Protein Name: | Cysteine and histidine-rich domain-containing protein 1 |
| UniProt Synonym Protein Names: | CHORD domain-containing protein 1; CHORD-containing protein 1; CHP-1; Protein morgana |
| Protein Family: | Cysteine and histidine-rich domain-containing protein |
| UniProt Gene Name: | CHORDC1 |
| UniProt Entry Name: | CHRD1_HUMAN |
 | Western blot analysis of extracts of mouse thymus, using CHORDC1 antibody (CAB17135) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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