Anti-CHIC2 Antibody (CAB7971)
- SKU:
- CAB7971
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | CHIC2 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB7971 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human CHIC2 (NP_036242.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human CHIC2 (NP_036242.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MADF DEIY EEEE DEER ALEE QLLK YSPD PVVV RGSG HVTV FGLS NKFE SEFP SSLT GKVA PEEF KASI NRVN SCLK KNLP VNVR WLLC GCLC CCCT LGCS MWPV ICLS KRTR RSIE KLLE WENN RLYH KLCL HWRL SKRK CETN NMME YVIL IEFL PKTP IFRP D |
| Gene ID: | 26511 |
| Uniprot: | Q9UKJ5 |
| Cellular Location: | Cell membrane, Cytoplasmic vesicle |
| Calculated MW: | 19kDa |
| Observed MW: | 19kDa |
| Synonyms: | CHIC2, BTL |
| Background: | This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. |
| UniProt Protein Function: | Subcellular location: Cell membrane. Cytoplasmic vesicle. Note: Also present at a Golgi-like vesicular compartment and at scattered vesicles. Ref.5 |
| UniProt Protein Details: | Post-translational modification: Palmitoylation in the CHIC motif is required for membrane association. Ref.5 Involvement in Disease: A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6. Sequence similarities: Belongs to the CHIC family. |
| NCBI Summary: | This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UKJ5 |
| NCBI GenInfo Identifier: | 6912276 |
| NCBI Gene ID: | 26511 |
| NCBI Accession: | NP_036242.1 |
| UniProt Secondary Accession: | Q9UKJ5,B2R639, |
| UniProt Related Accession: | Q9UKJ5 |
| Molecular Weight: | 19,254 Da |
| NCBI Full Name: | cysteine-rich hydrophobic domain 2 protein |
| NCBI Synonym Full Names: | cysteine-rich hydrophobic domain 2 |
| NCBI Official Symbol: | CHIC2 |
| NCBI Official Synonym Symbols: | BTL |
| NCBI Protein Information: | cysteine-rich hydrophobic domain 2 protein; BRX-like translocated in leukemia; cystein-rich hydrophobic domain 2 |
| UniProt Protein Name: | Cysteine-rich hydrophobic domain 2 protein |
| UniProt Synonym Protein Names: | BrX-like translocated in leukemia |
| Protein Family: | Cysteine-rich hydrophobic domain-containing protein |
| UniProt Gene Name: | CHIC2 |
| UniProt Entry Name: | CHIC2_HUMAN |
 | Western blot analysis of extracts of mouse testis, using CHIC2 Antibody (CAB7971) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human stomach using CHIC2 antibody (CAB7971) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat brain using CHIC2 antibody (CAB7971) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse brain using CHIC2 antibody (CAB7971) at dilution of 1:100 (40x lens). |
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