Anti-CHD7 Antibody (CAB17180)
- SKU:
- CAB17180
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Description
| Antibody Name: | Anti-CHD7 Antibody |
| Antibody SKU: | CAB17180 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CHD7 (NP_060250.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CHD7 (NP_060250.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MADP GMMS LFGE DGNI FSEG LEGL GECG YPEN PVNP MGQQ MPID QGFA SLQP SLHH PSTN QNQT KLTH FDHY NQYE QQKM HLMD QPNR MMSN TPGN GLAS PHSQ YHTP PVPQ VPHG GSGG GQMG VYPG MQNE RHGQ SFVD SSSM WGPR AVQV PDQI RAPY QQQQ PQPQ PPQP APSG PPAQ GHPQ HMQQ MGSY MARG DFSM QQHG QPQQ RMSQ FSQG QEGL NQGN PFIA TSGP GHLS HVPQ QSPS MAPS LRHS VQQF HHHP STAL HGES VAHS PRFS PNPP QQGA VRPQ TLNF SSRS QTVP |
| Gene ID: | 55636 |
| Uniprot: | Q9P2D1 |
| Cellular Location: | |
| Calculated MW: | 335kDa |
| Observed MW: | 335kDa |
 | Western blot - CHD7 Polyclonal Antibody (CAB17180) |
| Synonyms: | CHD7, CRG, HH5, IS3, KAL5 |
| Background: | This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | CHD-7: Probable transcription regulator. May interact with CTCF. Interacts with CHD8. Widely expressed in fetal and adult tissues. Belongs to the SNF2/RAD54 helicase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Helicase; DNA-binding; EC 3.6.4.12; Nucleolus Chromosomal Location of Human Ortholog: 8q12.2 Cellular Component: nucleolus; nucleus Molecular Function:ATP binding; chromatin binding; helicase activity; protein binding Biological Process: adult heart development; adult walking behavior; artery morphogenesis; blood circulation; central nervous system development; chromatin modification; cognition; cranial nerve development; embryonic hindlimb morphogenesis; female genitalia development; genitalia development; heart morphogenesis; in utero embryonic development; inner ear morphogenesis; limb development; nose development; olfactory behavior; olfactory bulb development; olfactory nerve development; palate development; positive regulation of multicellular organism growth; regulation of growth hormone secretion; regulation of neurogenesis; regulation of transcription, DNA-dependent; retina development in camera-type eye; rRNA processing; semicircular canal morphogenesis; sensory perception of sound; skeletal development; T cell differentiation; transcription, DNA-dependent Disease: Charge Syndrome; Hypogonadotropic Hypogonadism 5 With Or Without Anosmia; Tracheoesophageal Fistula With Or Without Esophageal Atresia |
| NCBI Summary: | This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
| UniProt Code: | Q9P2D1 |
| NCBI GenInfo Identifier: | 54112403 |
| NCBI Gene ID: | 55636 |
| NCBI Accession: | NP_060250.2 |
| UniProt Secondary Accession: | Q9P2D1,Q05DI5, Q2TAN4, Q66K35, Q7Z6C0, Q7Z7Q2, Q9NXA0 Q9NXA3, D0VBA5, E9PNZ2, |
| UniProt Related Accession: | Q9P2D1 |
| Molecular Weight: | 101,085 Da |
| NCBI Full Name: | chromodomain-helicase-DNA-binding protein 7 isoform 1 |
| NCBI Synonym Full Names: | chromodomain helicase DNA binding protein 7 |
| NCBI Official Symbol: | CHD7 |
| NCBI Official Synonym Symbols: | CRG; HH5; IS3; KAL5 |
| NCBI Protein Information: | chromodomain-helicase-DNA-binding protein 7 |
| UniProt Protein Name: | Chromodomain-helicase-DNA-binding protein 7 |
| UniProt Synonym Protein Names: | ATP-dependent helicase CHD7 |
| Protein Family: | Chromodomain-helicase-DNA-binding protein |
| UniProt Gene Name: | CHD7 |
| UniProt Entry Name: | CHD7_HUMAN |
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