Anti-CGB7 Antibody (CAB8522)
- SKU:
- CAB8522
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CGB7 Antibody |
| Antibody SKU: | CAB8522 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-165 of human CGB7 (NP_149133.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, MCF7, Mouse ovary, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-165 of human CGB7 (NP_149133.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SREM LRPR CRPI NATL AVEK EGCP VCIT VNTT ICAG YCPT MTRV LQGV LPAL PQVV CNYR DVRF ESIR LPGC PRGV NPVV SYAV ALSC QCAL CRRS TTDC GGPK DHPL TCDD PRFQ ASSS SKAP PPSL PSPS RLPG PSDT PILP Q |
| Gene ID: | 94027 |
| Uniprot: | P0DN87 |
| Cellular Location: | Secreted |
| Calculated MW: | 18kDa |
| Observed MW: | 18kDa |
| Synonyms: | CGB7, CG-beta-a, CGB6 |
| Background: | This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. |
| UniProt Protein Function: | CGB7: Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha- subunit is identical to the pituitary gonadotropin hormones (LH, FSH and TSH). The beta-subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role for pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. {ECO:0000305}. Belongs to the glycoprotein hormones subunit beta family. {ECO:0000305}. Heterodimer of a common alpha chain identical to LH, FSH, TSH and HCG and a unique beta chain distinct in each of the hormones and confer receptor and biological specificity. {ECO:0000305} |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19q13.33 Biological Process: apoptosis; cell-cell signaling; female gamete generation; signal transduction |
| NCBI Summary: | This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P0DN87 |
| NCBI GenInfo Identifier: | 1027923600 |
| NCBI Gene ID: | 94027 |
| NCBI Accession: | P0DN87.1 |
| UniProt Secondary Accession: | P0DN87,P01233, Q13991, Q14000, Q3KPI3, Q3SY41, Q8WTT5 Q8WXL1, Q8WXL2, Q8WXL3, A1A5E0, B9ZVP5, |
| UniProt Related Accession: | P0DN87 |
| Molecular Weight: | 18kDa |
| NCBI Full Name: | Choriogonadotropin subunit beta 7 |
| NCBI Synonym Full Names: | chorionic gonadotropin beta subunit 7 |
| NCBI Official Symbol: | CGB7 |
| NCBI Official Synonym Symbols: | CGB6; CG-beta-a |
| NCBI Protein Information: | choriogonadotropin subunit beta 7 |
| UniProt Protein Name: | Choriogonadotropin subunit beta 7 |
| Protein Family: | Choriogonadotropin |
| UniProt Gene Name: | CGB7 |
 | Western blot analysis of extracts of various cell lines, using CGB7 antibody (CAB8522) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse kidney using CGB7 antibody (CAB8522) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using CGB7 antibody (CAB8522) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using CGB7 antibody (CAB8522) at dilution of 1:100 (40x lens). |
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