Anti-CETN1 Antibody (CAB3784)
- SKU:
- CAB3784
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-CETN1 Antibody |
| Antibody SKU: | CAB3784 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CETN1 (NP_004057.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, Jurkat, MCF7, THP-1, HeLa, Mouse testis, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CETN1 (NP_004057.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MASG FKKP SAAS TGQK RKVA PKPE LTED QKQE VREA FDLF DVDG SGTI DAKE LKVA MRAL GFEP RKEE MKKM ISEV DREG TGKI SFND FLAV MTQK MSEK DTKE EILK AFRL FDDD ETGK ISFK NLKR VANE LGEN LTDE ELQE MIDE ADRD GDGE VNEE EFLR IMKK TSLY |
| Gene ID: | 1068 |
| Uniprot: | Q12798 |
| Cellular Location: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center |
| Calculated MW: | 19kDa |
| Observed MW: | 20kDa |
| Synonyms: | CETN1, CEN1, CETN, centrin-1 |
| Background: | The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. |
| UniProt Protein Function: | CETN1: Plays a fundamental role in microtubule-organizing center structure and function. Belongs to the centrin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 18p11.32 Cellular Component: centriole; spindle pole; centrosome; photoreceptor connecting cilium Molecular Function:protein binding; microtubule binding; G-protein beta/gamma-subunit binding; calcium ion binding; heterotrimeric G-protein binding Biological Process: mitosis; cell division |
| NCBI Summary: | The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jan 2015] |
| UniProt Code: | Q12798 |
| NCBI GenInfo Identifier: | 2493440 |
| NCBI Gene ID: | 1068 |
| NCBI Accession: | Q12798.1 |
| UniProt Secondary Accession: | Q12798,B2R536, |
| UniProt Related Accession: | Q12798 |
| Molecular Weight: | 172 |
| NCBI Full Name: | Centrin-1 |
| NCBI Synonym Full Names: | centrin, EF-hand protein, 1 |
| NCBI Official Symbol: | CETN1 |
| NCBI Official Synonym Symbols: | CEN1; CETN |
| NCBI Protein Information: | centrin-1; caltractin; EF-hand protein; calcium binding protein |
| UniProt Protein Name: | Centrin-1 |
| UniProt Synonym Protein Names: | Caltractin isoform 2 |
| Protein Family: | Centrin |
| UniProt Gene Name: | CETN1 |
| UniProt Entry Name: | CETN1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CETN1 antibody (CAB3784) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunohistochemistry of paraffin-embedded human liver damage using CETN1 antibody (CAB3784) at dilution of 1:100 (40x lens). |
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