Anti-CEBPD Antibody (CAB15261)
- SKU:
- CAB15261
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-CEBPD Antibody |
| Antibody SKU: | CAB15261 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human CEBPD (NP_005186.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human CEBPD (NP_005186.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSAA LFSL DGPA RGAP WPAE PAPF YEPG RAGK PGRG AEPG ALGE PGAA APAM YDDE SAID FSAY IDSM AAVP TLEL CHDE LFAD LFNS NHKA GGAG PLEL LPGG PARP LGPG PAAP RLLK REPD WGDG DAPG SLLP AQVA ACAQ TVVS LAAA GQPT PPTS PEPP RSSP RQTP APGP AREK SAGK RGPD RGSP EYRQ RRER NNIA VRKS RDKA KRRN QEMQ QKLV ELSA ENEK LHQR VEQL TRDL AGLR QFFK QLPS PPFL PAAG TADC R |
| Gene ID: | 1052 |
| Uniprot: | P49716 |
| Cellular Location: | Nucleus |
| Calculated MW: | 28kDa |
| Observed MW: | 28kDa |
| Synonyms: | CEBPD, C/EBP-delta, CELF, CRP3, NF-IL6-beta |
| Background: | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. |
| UniProt Protein Function: | C/EBP-delta: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1. Interacts with PRDM16. Belongs to the bZIP family. C/EBP subfamily. |
| UniProt Protein Details: | Protein type:DNA-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 8p11.2-p11.1 Cellular Component: nucleus Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010] |
| UniProt Code: | P49716 |
| NCBI GenInfo Identifier: | 160332350 |
| NCBI Gene ID: | 1052 |
| NCBI Accession: | P49716.2 |
| UniProt Secondary Accession: | P49716,Q03484, |
| UniProt Related Accession: | P49716 |
| Molecular Weight: | 269 |
| NCBI Full Name: | CCAAT/enhancer-binding protein delta |
| NCBI Synonym Full Names: | CCAAT/enhancer binding protein (C/EBP), delta |
| NCBI Official Symbol: | CEBPD |
| NCBI Official Synonym Symbols: | CELF; CRP3; C/EBP-delta; NF-IL6-beta |
| NCBI Protein Information: | CCAAT/enhancer-binding protein delta; c/EBP delta; nuclear factor NF-IL6-beta |
| UniProt Protein Name: | CCAAT/enhancer-binding protein delta |
| UniProt Synonym Protein Names: | Nuclear factor NF-IL6-beta; NF-IL6-beta |
| Protein Family: | CCAAT/enhancer-binding protein |
| UniProt Gene Name: | CEBPD |
| UniProt Entry Name: | CEBPD_HUMAN |
 | Western blot analysis of extracts of mouse lung, using CEBPD antibody (CAB15261) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90S. |
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