Anti-CDX1 Antibody (CAB5712)
- SKU:
- CAB5712
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Antibody Name: | Anti-CDX1 Antibody |
Antibody SKU: | CAB5712 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 136-265 of human CDX1 (NP_001795.2). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse |
Positive Samples: | Mouse liver, Mouse heart |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 136-265 of human CDX1 (NP_001795.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MRRS VAAG GGGG SGKT RTKD KYRV VYTD HQRL ELEK EFHY SRYI TIRR KSEL AANL GLTE RQVK IWFQ NRRA KERK VNKK KQQQ QQPP QPPM AHDI TATP AGPS LGGL CPSN TSLL ATSS PMPV KEEF LP |
Gene ID: | 1044 |
Uniprot: | P47902 |
Cellular Location: | Nucleus |
Calculated MW: | 14kDa/28kDa |
Observed MW: | 35kDa |
Synonyms: | CDX1 |
Background: | This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. |
UniProt Protein Function: | CDX1: Could play a role in the terminal differentiation of the intestine. Belongs to the Caudal homeobox family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 5q32 Cellular Component: nucleus Molecular Function:protein binding Biological Process: anterior/posterior axis specification; cell differentiation; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of somitogenesis |
NCBI Summary: | This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008] |
UniProt Code: | P47902 |
NCBI GenInfo Identifier: | 116241291 |
NCBI Gene ID: | 1044 |
NCBI Accession: | P47902.2 |
UniProt Secondary Accession: | P47902,Q4VAU4, Q9NYK8, |
UniProt Related Accession: | P47902 |
Molecular Weight: | 14,661 Da |
NCBI Full Name: | Homeobox protein CDX-1 |
NCBI Synonym Full Names: | caudal type homeobox 1 |
NCBI Official Symbol: | CDX1 |
NCBI Protein Information: | homeobox protein CDX-1 |
UniProt Protein Name: | Homeobox protein CDX-1 |
UniProt Synonym Protein Names: | Caudal-type homeobox protein 1 |
Protein Family: | Homeobox protein |
UniProt Gene Name: | CDX1 |
UniProt Entry Name: | CDX1_HUMAN |