Anti-CDHR5 Antibody (CAB13850)
- SKU:
- CAB13850
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CDHR5 Antibody |
| Antibody SKU: | CAB13850 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-220 of human CDHR5 (NP_112554.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse kidney, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-220 of human CDHR5 (NP_112554.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QAQY CSVN KDIF EVEE NTNV TEPL VDIH VPEG QEVT LGAL STPF AFRI QGNQ LFLN VTPD YEEK SLLE AQLL CQSG GTLV TQLR VFVS VLDV NDNA PEFP FKTK EIRV EEDT KVNS TVIP ETQL QAED RDKD DILF YTLQ EMTA GASD YFSL VSVN RPAL RLDR PLDF YERP NMTF WLLV RDTP GENV EPSH TAT |
| Gene ID: | 53841 |
| Uniprot: | Q9HBB8 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 69kDa/87kDa/88kDa |
| Observed MW: | 88kDa |
| Synonyms: | CDHR5, MLPCDH, MU-PCDH, MUCDHL, MUPCDH |
| Background: | This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. |
| UniProt Protein Function: | MUCDHL: Acts as a calcium-dependent cell adhesion protein. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: apical plasma membrane; brush border membrane; microvillus membrane Molecular Function:beta-catenin binding; calcium ion binding; cell adhesion molecule binding; protein binding Biological Process: cell adhesion; regulation of microvillus length |
| NCBI Summary: | This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010] |
| UniProt Code: | Q9HBB8 |
| NCBI GenInfo Identifier: | 296439399 |
| NCBI Gene ID: | 53841 |
| NCBI Accession: | Q9HBB8.3 |
| UniProt Secondary Accession: | Q9HBB8,Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86 Q9NXI9, C9J7X1, |
| UniProt Related Accession: | Q9HBB8 |
| Molecular Weight: | 87,631 Da |
| NCBI Full Name: | Cadherin-related family member 5 |
| NCBI Synonym Full Names: | cadherin related family member 5 |
| NCBI Official Symbol: | CDHR5 |
| NCBI Official Synonym Symbols: | MLPCDH; MUCDHL; MUPCDH; MU-PCDH |
| NCBI Protein Information: | cadherin-related family member 5 |
| UniProt Protein Name: | Cadherin-related family member 5 |
| UniProt Synonym Protein Names: | Mu-protocadherin |
| Protein Family: | Cadherin-related family |
| UniProt Gene Name: | CDHR5 |
| UniProt Entry Name: | CDHR5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CDHR5 antibody (CAB13850) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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