Anti-CDC42EP3 Antibody (CAB8480)
- SKU:
- CAB8480
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Antibody Name: | Anti-CDC42EP3 Antibody |
Antibody SKU: | CAB8480 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T, K-562, NIH/3T3, Rat heart |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MPAK TPIY LKAA NNKK GKKF KLRD ILSP DMIS PPLG DFRH TIHI GKEG QHDV FGDI SFLQ GNYE LLPG NQEK AHLG QFPG HNEF FRAN STSD SVFT ETPS PVLK NAIS LPTI GGSQ ALML PLLS PVTF NSKQ ESFG PAKL PRLS CEPV MEEK AQEK SSLL ENGT VHQG DTSW GSSG SASQ SSQG RDSH SSSL SEQY PDWP AEDM FDHP TPCE LIKG KTKS EESL SDLT GSLL SLQL DLGP SLLD EVLN VMDK NK |
Gene ID: | 10602 |
Uniprot: | Q9UKI2 |
Cellular Location: | Cytoplasm, Endomembrane system, Peripheral membrane protein, cytoskeleton |
Calculated MW: | 27kDa |
Observed MW: | 37kDa |
Synonyms: | CDC42EP3, BORG2, CEP3, UB1 |
Background: | This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. |
NCBI Summary: | This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
UniProt Code: | Q9UKI2 |
NCBI GenInfo Identifier: | 395627662 |
NCBI Gene ID: | 10602 |
NCBI Accession: | NP_001257365.1 |
UniProt Secondary Accession: | Q9UKI2,O95353, Q9UQJ0, B2R8S0, |
UniProt Related Accession: | Q9UKI2 |
Molecular Weight: | 27,678 Da |
NCBI Full Name: | cdc42 effector protein 3 |
NCBI Synonym Full Names: | CDC42 effector protein 3 |
NCBI Official Symbol: | CDC42EP3 |
NCBI Official Synonym Symbols: | UB1; CEP3; BORG2 |
NCBI Protein Information: | cdc42 effector protein 3 |
UniProt Protein Name: | Cdc42 effector protein 3 |
UniProt Synonym Protein Names: | Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein |
UniProt Gene Name: | CDC42EP3 |