| Synonyms: | CCT6A, CCT-zeta, CCT-zeta-1, CCT6, Cctz, HTR3, MoDP-2, TCP-1-zeta, TCP20, TCPZ, TTCP20 |
| Background: | The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. |
| UniProt Protein Function: | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. |
| NCBI Summary: | The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010] |
| UniProt Code: | P40227 |
| NCBI GenInfo Identifier: | 58331171 |
| NCBI Gene ID: | 908 |
| NCBI Accession: | NP_001009186.1 |
| UniProt Secondary Accession: | P40227,Q3KP28, Q75LP4, Q96S46, A6NCD2, |
| UniProt Related Accession: | P40227 |
| Molecular Weight: | 53,289 Da |
| NCBI Full Name: | T-complex protein 1 subunit zeta isoform b |
| NCBI Synonym Full Names: | chaperonin containing TCP1 subunit 6A |
| NCBI Official Symbol: | CCT6A |
| NCBI Official Synonym Symbols: | CCT6; Cctz; HTR3; TCPZ; TCP20; MoDP-2; TTCP20; CCT-zeta; CCT-zeta-1; TCP-1-zeta |
| NCBI Protein Information: | T-complex protein 1 subunit zeta |
| UniProt Protein Name: | T-complex protein 1 subunit zeta |
| UniProt Synonym Protein Names: | Acute morphine dependence-related protein 2; CCT-zeta-1; HTR3; Tcp20 |
| Protein Family: | T-complex protein |
| UniProt Gene Name: | CCT6A |
