Anti-CCL21 Antibody (CAB1896)

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SKU:
CAB1896
Product type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Frequently bought together:

Description

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Antibody Name:Anti-CCL21 Antibody
Antibody SKU:CAB1896
Antibody Size:20uL, 50uL, 100uL
Application:IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-134 of human CCL21 (NP_002980.1).
Application:IHC
Recommended Dilution:IHC 1:50 - 1:100
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-134 of human CCL21 (NP_002980.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SDGG AQDC CLKY SQRK IPAK VVRS YRKQ EPSL GCSI PAIL FLPR KRSQ AELC ADPK ELWV QQLM QHLD KTPS PQKP AQGC RKDR GASK TGKK GKGS KGCK RTER SQTP KGP
Gene ID:6366
Uniprot:O00585
Cellular Location:Secreted
Calculated MW:14kDa
Observed MW:
Synonyms:CCL21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4
Background:This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
NCBI Summary:This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]
UniProt Code:O00585
NCBI GenInfo Identifier:6094386
NCBI Gene ID:6366
NCBI Accession:O00585.1
UniProt Related Accession:O00585
Molecular Weight:
NCBI Full Name:C-C motif chemokine 21
NCBI Synonym Full Names:C-C motif chemokine ligand 21
NCBI Official Symbol:CCL21  
NCBI Official Synonym Symbols:ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21  
NCBI Protein Information:C-C motif chemokine 21
UniProt Protein Name:C-C motif chemokine 21
UniProt Synonym Protein Names:6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21
Protein Family:C-C motif chemokine
UniProt Gene Name:CCL21  
UniProt Entry Name:CCL21_HUMAN
Anti-CCL21 Antibody (CAB1896)Immunohistochemistry of paraffin-embedded human liver using CCL21 antibody (CAB1896) at dilution of 1:100 (40x lens).
Anti-CCL21 Antibody (CAB1896)Immunohistochemistry of paraffin-embedded human stomach using CCL21 antibody (CAB1896) at dilution of 1:100 (40x lens).

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