Anti-CCDC50 Antibody (CAB17836)
- SKU:
- CAB17836
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-CCDC50 Antibody |
| Antibody SKU: | CAB17836 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-147 of human CCDC50 (NP_777568.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, 293T, U-87MG, Mouse lung, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-147 of human CCDC50 (NP_777568.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KLPG VKEV CRDF AVLE DHTL AHSL QEQE IEHH LASN VQRN RLVQ HDLQ VAKQ LQEE DLKA QAQL QKRY KDLE QQDC EIAQ EIQE KLAI EAER RRIQ EKKD EDIA RLLQ EKEL QEEK KRKK HFPE FPAT RAYA DSYY YE |
| Gene ID: | 152137 |
| Uniprot: | Q8IVM0 |
| Cellular Location: | |
| Calculated MW: | 35kDa/56kDa |
| Observed MW: | 36kDa |
 | Western blot - CCDC50 Rabbit pAb (CAB17836) |
| Synonyms: | C3orf6, DFNA44, YMER, CCDC50 |
| Background: | This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| UniProt Protein Function: | Involved in EGFR signaling. |
| NCBI Summary: | This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| UniProt Code: | Q8IVM0 |
| NCBI GenInfo Identifier: | 73619722 |
| NCBI Gene ID: | 152137 |
| NCBI Accession: | Q8IVM0.1 |
| UniProt Secondary Accession: | Q8IVM0,Q86VH7, |
| UniProt Related Accession: | Q8IVM0 |
| Molecular Weight: | 56,340 Da |
| NCBI Full Name: | Coiled-coil domain-containing protein 50 |
| NCBI Synonym Full Names: | coiled-coil domain containing 50 |
| NCBI Official Symbol: | CCDC50 |
| NCBI Official Synonym Symbols: | YMER; C3orf6; DFNA44 |
| NCBI Protein Information: | coiled-coil domain-containing protein 50 |
| UniProt Protein Name: | Coiled-coil domain-containing protein 50 |
| UniProt Synonym Protein Names: | Protein Ymer |
| Protein Family: | Coiled-coil domain-containing protein |
| UniProt Gene Name: | CCDC50 |
| UniProt Entry Name: | CCD50_HUMAN |
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