Anti-CARTPT Antibody (CAB18275)
- SKU:
- CAB18275
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CARTPT Antibody |
| Antibody SKU: | CAB18275 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human CARTPT. |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant protein of human CARTPT. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9607 |
| Uniprot: | Q16568 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
 | Immunohistochemistry - CARTPT Polyclonal Antibody (CAB18275) |
| Synonyms: | CART, CARTPT |
| Background: |
| UniProt Protein Function: | CARTPT: Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro. Belongs to the CART family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Secreted; Hormone; Secreted, signal peptide Chromosomal Location of Human Ortholog: 5q13.2 Cellular Component: extracellular space; secretory granule Molecular Function:protein binding Biological Process: negative regulation of osteoclast differentiation; activation of MAPKK activity; adult feeding behavior; cellular response to starvation; signal transduction; negative regulation of appetite; G-protein coupled receptor protein signaling pathway; synaptic transmission; cell-cell signaling; neuropeptide signaling pathway; positive regulation of epinephrine secretion; cell glucose homeostasis; circadian regulation of gene expression; negative regulation of bone resorption; regulation of insulin secretion; positive regulation of blood pressure; positive regulation of transmission of nerve impulse Disease: Obesity |
| NCBI Summary: | This gene encodes a secreted protein which is processed by prohormone/proprotein convertases to produce smaller, biologically active peptides. Expression of the transcript for this gene is regulated by certain drugs such as cocaine, and the encoded protein is thought to be involved in the regulation of appetite and stress. Mutations in this gene are associated with susceptibility to obesity.[provided by RefSeq, Nov 2009] |
| UniProt Code: | Q16568 |
| NCBI GenInfo Identifier: | 2833274 |
| NCBI Gene ID: | 9607 |
| NCBI Accession: | Q16568.1 |
| UniProt Secondary Accession: | Q16568,Q6FG92, |
| UniProt Related Accession: | Q16568 |
| Molecular Weight: | 12,829 Da |
| NCBI Full Name: | Cocaine- and amphetamine-regulated transcript protein |
| NCBI Synonym Full Names: | CART prepropeptide |
| NCBI Official Symbol: | CARTPT |
| NCBI Official Synonym Symbols: | CART |
| NCBI Protein Information: | cocaine- and amphetamine-regulated transcript protein; cocaine and amphetamine regulated transcript |
| UniProt Protein Name: | Cocaine- and amphetamine-regulated transcript protein |
| Protein Family: | Cocaine- and amphetamine-regulated transcript protein |
| UniProt Gene Name: | CARTPT |
| UniProt Entry Name: | CART_HUMAN |
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