Anti-CAPN7 Antibody (CAB17666)
- SKU:
- CAB17666
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-CAPN7 Antibody |
| Antibody SKU: | CAB17666 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human CAPN7 (NP_055111.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human CAPN7 (NP_055111.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RDHE GRYS EAVF YYKE AAQA LIYA EMAG SSLE NIQE KITE YLER VQAL HSAV QSKS ADPL KSKH QLDL ERAH FLVT QAFD EDEK ENVE DAIE LYTE AVDL CLKT SYET ADKV LQNK LKQL ARQA LDRA EALS EPLT KPVG KISS TSVK PKPP PVRA HFPL GANP FLER PQSF ISPQ SCDA QGQR YTAE EIEV LRTT SKIN G |
| Gene ID: | 23473 |
| Uniprot: | Q9Y6W3 |
| Cellular Location: | |
| Calculated MW: | 92kDa |
| Observed MW: | 93kDa |
 | Western blot - CAPN7 Rabbit pAb (CAB17666) |
| Synonyms: | CALPAIN7, PALBH, CAPN7, calpain-7 |
| Background: | Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | Calcium-regulated non-lysosomal thiol-protease. |
| NCBI Summary: | Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y6W3 |
| NCBI GenInfo Identifier: | 7656959 |
| NCBI Gene ID: | 23473 |
| NCBI Accession: | NP_055111.1 |
| UniProt Related Accession: | Q9Y6W3 |
| Molecular Weight: | |
| NCBI Full Name: | calpain-7 |
| NCBI Synonym Full Names: | calpain 7 |
| NCBI Official Symbol: | CAPN7 |
| NCBI Official Synonym Symbols: | PALBH; CALPAIN7 |
| NCBI Protein Information: | calpain-7 |
| UniProt Protein Name: | Calpain-7 |
| UniProt Synonym Protein Names: | PalB homolog; PalBH |
| UniProt Gene Name: | CAPN7 |
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