| Synonyms: | CAMP, CAP-18, CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37 |
| Background: | This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014] |
| UniProt Protein Function: | CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Cell cycle regulation; Vesicle; Secreted Chromosomal Location of Human Ortholog: 3p21.3 Cellular Component: cell wall; extracellular region; extracellular space; specific granule Biological Process: antibacterial humoral response; cell redox homeostasis; defense response to bacterium; defense response to Gram-positive bacterium; innate immune response in mucosa; killing by host of symbiont cells |
| NCBI Summary: | This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014] |
| UniProt Code: | P49913 |
| NCBI GenInfo Identifier: | 1706745 |
| NCBI Gene ID: | 820 |
| NCBI Accession: | P49913.1 |
| UniProt Secondary Accession: | P49913,Q71SN9, |
| UniProt Related Accession: | P49913 |
| Molecular Weight: | 19,301 Da |
| NCBI Full Name: | Cathelicidin antimicrobial peptide |
| NCBI Synonym Full Names: | cathelicidin antimicrobial peptide |
| NCBI Official Symbol: | CAMP |
| NCBI Official Synonym Symbols: | LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39 |
| NCBI Protein Information: | cathelicidin antimicrobial peptide |
| UniProt Protein Name: | Cathelicidin antimicrobial peptide |
| UniProt Synonym Protein Names: | FALL-39 peptide antibiotic |
| Protein Family: | CAMPATH-1 antigen |
| UniProt Gene Name: | CAMP |
| UniProt Entry Name: | CAMP_HUMAN |
