Anti-CAMK1 Antibody (CAB14495)
- SKU:
- CAB14495
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
Antibody Name: | Anti-CAMK1 Antibody |
Antibody SKU: | CAB14495 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human CAMK1 (NP_003647.1). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Mouse lung, Rat liver |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human CAMK1 (NP_003647.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MLGA VEGP RWKQ AEDI RDIY DFRD VLGT GAFS EVIL AEDK RTQK LVAI KCIA KEAL EGKE GSME NEIA VLHK IKHP NIVA LDDI YESG GHLY L |
Gene ID: | 8536 |
Uniprot: | Q14012 |
Cellular Location: | Cytoplasm, Nucleus |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |
Synonyms: | CAMK1, CAMKI |
Background: | Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. |
UniProt Protein Function: | CAMK1A: an ubiquitous protein kinase of the CAMK1 family. Activated by Ca(2+)/calmodulin. Must be phosphorylated to be maximally active. Substrates include synapsin I. |
UniProt Protein Details: | Protein type:Kinase, protein; EC 2.7.11.17; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; CAMK1 family Chromosomal Location of Human Ortholog: 3p25.3 Cellular Component: cytoplasm; nucleus Molecular Function:calmodulin binding; protein binding; calmodulin-dependent protein kinase activity; ATP binding Biological Process: positive regulation of syncytium formation by plasma membrane fusion; regulation of muscle cell differentiation; nucleocytoplasmic transport; signal transduction; cell cycle; protein amino acid phosphorylation; positive regulation of peptidyl-serine phosphorylation; positive regulation of synapse structural plasticity; positive regulation of protein export from nucleus; regulation of protein localization; regulation of protein binding; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of protein binding |
NCBI Summary: | Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14012 |
NCBI GenInfo Identifier: | 3122301 |
NCBI Gene ID: | 8536 |
NCBI Accession: | Q14012.1 |
UniProt Secondary Accession: | Q14012,Q3KPF6, |
UniProt Related Accession: | Q14012 |
Molecular Weight: | 370 |
NCBI Full Name: | Calcium/calmodulin-dependent protein kinase type 1 |
NCBI Synonym Full Names: | calcium/calmodulin-dependent protein kinase I |
NCBI Official Symbol: | CAMK1 |
NCBI Official Synonym Symbols: | CAMKI |
NCBI Protein Information: | calcium/calmodulin-dependent protein kinase type 1; caM-KI; caMKI-alpha; caM kinase I alpha |
UniProt Protein Name: | Calcium/calmodulin-dependent protein kinase type 1 |
UniProt Synonym Protein Names: | CaM kinase I; CaM-KI; CaM kinase I alpha; CaMKI-alpha |
Protein Family: | Calcium/calmodulin-dependent serine/threonine-protein kinase |
UniProt Gene Name: | CAMK1 |
UniProt Entry Name: | KCC1A_HUMAN |