Anti-CACNG1 Antibody (CAB10014)
- SKU:
- CAB10014
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CACNG1 Antibody |
| Antibody SKU: | CAB10014 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human CACNG1 (NP_000718.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:4000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse skeletal muscle, Mouse liver, Mouse kidney, Rat skeletal muscle, Rat liver, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-110 of human CACNG1 (NP_000718.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DHWA VLSP HMEH HNTT CEAA HFGL WRIC TKRI PMDD SKTC GPIT LPGE KNCS YFRH FNPG ESSE IFEF TTQK EYSI SAAA I |
| Gene ID: | 786 |
| Uniprot: | Q06432 |
| Cellular Location: | Membrane, Multi-pass membrane protein |
| Calculated MW: | 25kDa |
| Observed MW: | 23kDa |
| Synonyms: | CACNG1, CACNLG |
| Background: | Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1, 4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). |
| UniProt Protein Function: | CACNG1: This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 17q24 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: muscle contraction; transport |
| NCBI Summary: | Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q06432 |
| NCBI GenInfo Identifier: | 1168946 |
| NCBI Gene ID: | 786 |
| NCBI Accession: | Q06432.1 |
| UniProt Secondary Accession: | Q06432,Q14D59, B2R9N3, |
| UniProt Related Accession: | Q06432 |
| Molecular Weight: | 25,028 Da |
| NCBI Full Name: | Voltage-dependent calcium channel gamma-1 subunit |
| NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit gamma 1 |
| NCBI Official Symbol: | CACNG1 |
| NCBI Official Synonym Symbols: | CACNLG |
| NCBI Protein Information: | voltage-dependent calcium channel gamma-1 subunit |
| UniProt Protein Name: | Voltage-dependent calcium channel gamma-1 subunit |
| UniProt Synonym Protein Names: | Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma |
| Protein Family: | Voltage-dependent calcium channel |
| UniProt Gene Name: | CACNG1 |
| UniProt Entry Name: | CCG1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CACNG1 antibody (CAB10014) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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