Anti-C3AR1 Antibody (CAB6361)
- SKU:
- CAB6361
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-C3AR1 Antibody |
| Antibody SKU: | CAB6361 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-337 of human C3AR1 (NP_004045.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, HT-29, Mouse spleen, Mouse lung, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-337 of human C3AR1 (NP_004045.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | REIF TTDN HNRC GYKF GLSS SLDY PDFY GDPL ENRS LENI VQPP GEMN DRLD PSSF QTND HPWT VPTV FQPQ TFQR PSAD SLPR GSAR LTSQ NLYS NVFK PADV VSPK IPSG FPIE DHET SPLD NSDA FLST HLKL FPSA SSNS FYES ELPQ GFQD YYNL GQFT DDDQ VPTP LVAI T |
| Gene ID: | 719 |
| Uniprot: | Q16581 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 53kDa |
| Observed MW: | 55kDa |
| Synonyms: | C3AR1, AZ3B, C3AR, HNFAG09 |
| Background: |
| UniProt Protein Function: | C3aR: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR Chromosomal Location of Human Ortholog: 12p13.31 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; C3a anaphylatoxin receptor activity; complement component C3a receptor activity; phosphoinositide phospholipase C activity Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; elevation of cytosolic calcium ion concentration; metabolic process; blood circulation; complement receptor mediated signaling pathway; chemotaxis; inflammatory response |
| UniProt Code: | Q16581 |
| NCBI GenInfo Identifier: | 37538305 |
| NCBI Gene ID: | 719 |
| NCBI Accession: | Q16581.2 |
| UniProt Secondary Accession: | Q16581,O43771, Q92868, |
| UniProt Related Accession: | Q16581 |
| Molecular Weight: | 482 |
| NCBI Full Name: | C3a anaphylatoxin chemotactic receptor |
| NCBI Synonym Full Names: | complement component 3a receptor 1 |
| NCBI Official Symbol: | C3AR1 |
| NCBI Official Synonym Symbols: | AZ3B; C3AR; HNFAG09 |
| NCBI Protein Information: | C3a anaphylatoxin chemotactic receptor; C3a-R; complement component 3 receptor 1 |
| UniProt Protein Name: | C3a anaphylatoxin chemotactic receptor |
| Protein Family: | C3a anaphylatoxin chemotactic receptor |
| UniProt Gene Name: | C3AR1 |
| UniProt Entry Name: | C3AR_HUMAN |
 | Western blot analysis of extracts of various cell lines, using C3AR1 Antibody (CAB6361) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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