Anti-BRINP3 Antibody (CAB18237)
- SKU:
- CAB18237
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-BRINP3 Antibody |
| Antibody SKU: | CAB18237 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human BRINP3. |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, Mouse brain |
| Immunogen: | Recombinant protein of human BRINP3. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 339479 |
| Uniprot: | Q76B58 |
| Cellular Location: | |
| Calculated MW: | 88kDa |
| Observed MW: | 88kDa |
 | Western blot - BRINP3 Rabbit pAb (CAB18237) |
| Synonyms: | FAM5C, DBCCR1L, DBCCR1L1, BRINP3 |
| Background: | This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | FAM5C: Belongs to the FAM5 family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 1q31.1 Biological Process: negative regulation of mitotic cell cycle; positive regulation of neuron differentiation |
| NCBI Summary: | This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
| UniProt Code: | Q76B58 |
| NCBI GenInfo Identifier: | 74749831 |
| NCBI Gene ID: | 339479 |
| NCBI Accession: | Q76B58.1 |
| UniProt Secondary Accession: | Q76B58,O95726, Q2M330, B3KVP1, B7Z260, |
| UniProt Related Accession: | Q76B58 |
| Molecular Weight: | 76,299 Da |
| NCBI Full Name: | BMP/retinoic acid-inducible neural-specific protein 3 |
| NCBI Synonym Full Names: | BMP/retinoic acid inducible neural specific 3 |
| NCBI Official Symbol: | BRINP3 |
| NCBI Official Synonym Symbols: | FAM5C; DBCCR1L; DBCCR1L1 |
| NCBI Protein Information: | BMP/retinoic acid-inducible neural-specific protein 3 |
| UniProt Protein Name: | BMP/retinoic acid-inducible neural-specific protein 3 |
| UniProt Synonym Protein Names: | DBCCR1-like protein 1 |
| Protein Family: | BMP/retinoic acid-inducible neural-specific protein |
| UniProt Gene Name: | BRINP3 |
| UniProt Entry Name: | BRNP3_HUMAN |
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