Anti-BOK Antibody (CAB16354)
- SKU:
- CAB16354
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-BOK Antibody |
| Antibody SKU: | CAB16354 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BOK (NP_115904.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BOK (NP_115904.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEVL RRSS VFAA EIMD AFDR SPTD KELV AQAK ALGR EYVH ARLL RAGL SWSA PERA APVP GRLA EVCA VLLR LGDE LEMI RPSV YRNV ARQL HISL QSEP |
| Gene ID: | 666 |
| Uniprot: | Q9UMX3 |
| Cellular Location: | Endoplasmic reticulum membrane, Golgi apparatus membrane, Single-pass membrane protein |
| Calculated MW: | 14kDa/23kDa |
| Observed MW: | Refer to figures |
| Synonyms: | BOK, BCL2L9, BOKL |
| Background: | The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. |
| UniProt Protein Function: | BOK: May play a role in apoptosis. Belongs to the Bcl-2 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: cytoplasm; mitochondrial membrane; mitochondrial outer membrane; mitochondrion; nucleus Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity Biological Process: apoptosis; caspase activation; cell proliferation; DNA damage response, signal transduction resulting in induction of apoptosis |
| NCBI Summary: | The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011] |
| UniProt Code: | Q9UMX3 |
| NCBI GenInfo Identifier: | 57012554 |
| NCBI Gene ID: | 666 |
| NCBI Accession: | Q9UMX3.1 |
| UniProt Related Accession: | Q9UMX3 |
| Molecular Weight: | 23,280 Da |
| NCBI Full Name: | Bcl-2-related ovarian killer protein |
| NCBI Synonym Full Names: | BOK, BCL2 family apoptosis regulator |
| NCBI Official Symbol: | BOK |
| NCBI Official Synonym Symbols: | BOKL; BCL2L9 |
| NCBI Protein Information: | bcl-2-related ovarian killer protein |
| UniProt Protein Name: | Bcl-2-related ovarian killer protein |
| UniProt Synonym Protein Names: | Bcl-2-like protein 9; Bcl2-L-9 |
| Protein Family: | Bcl-2-related ovarian killer protein |
| UniProt Gene Name: | BOK |
| UniProt Entry Name: | BOK_HUMAN |
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