Anti-BGAT Antibody (CAB5207)
- SKU:
- CAB5207
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-BGAT Antibody |
| Antibody SKU: | CAB5207 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human BGAT |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HT-29, THP-1 |
| Immunogen: | A synthesized peptide derived from human BGAT |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 28 |
| Uniprot: | P16442 |
| Cellular Location: | |
| Calculated MW: | 41kDa |
| Observed MW: | 41KDa |
| Synonyms: | A3GALNT, A3GALT1, GTB, NAGAT |
| Background: | This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | ABO: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Belongs to the glycosyltransferase 6 family. |
| UniProt Protein Details: | Protein type:Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.1.37; Membrane protein, integral; EC 2.4.1.40; Transferase Chromosomal Location of Human Ortholog: 9q34.2 Cellular Component: integral to membrane; extracellular region Molecular Function:metal ion binding; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity; fucosylgalactoside 3-alpha-galactosyltransferase activity Biological Process: protein amino acid glycosylation Disease: Blood Group, Abo System |
| NCBI Summary: | This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P16442 |
| NCBI GenInfo Identifier: | 114949 |
| NCBI Gene ID: | 28 |
| NCBI Accession: | P16442.2 |
| UniProt Related Accession: | P16442 |
| Molecular Weight: | |
| NCBI Full Name: | Histo-blood group ABO system transferase |
| NCBI Synonym Full Names: | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase |
| NCBI Official Symbol: | ABO |
| NCBI Official Synonym Symbols: | GTB; NAGAT; A3GALNT; A3GALT1 |
| NCBI Protein Information: | histo-blood group ABO system transferase |
| UniProt Protein Name: | Histo-blood group ABO system transferase |
| UniProt Synonym Protein Names: | Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase (EC:2.4.1.40); Glycoprotein-fucosylgalactoside alpha-galactosyltransferase (EC:2.4.1.37); Histo-blood group A transferase; A transferase; Histo-blood group B transferase; B transferase; NAGATFucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form |
| Protein Family: | 4-methylaminobutanoate oxidase |
| UniProt Gene Name: | ABO |
| UniProt Entry Name: | BGAT_HUMAN |
 | Western blot - BGAT Rabbit mAb (CAB5207) |
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