Anti-BCAS2 Antibody (CAB4398)

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SKU:
CAB4398
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
BCAS2
DAM1
SPF27
Snt309
Frequently bought together:

Description

Product Name:BCAS2 Rabbit pAb
Product Code:CAB4398
Size:20uL, 50uL, 100uL
Synonyms:BCAS2, DAM1, SPF27, Snt309
Applications:WB, IHC, IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1).
Applications:WB, IHC, IF
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, Jurkat, MCF-7, HeLa, SKOV3, Mouse testis, Mouse spleen, Mouse lung, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAGT GLVA GEVV VDAL PYFD QGYE APGV REAA AALV EEET RRYR PTKN YLSY LTAP DYSA FETD IMRN EFER LAAR QPIE LLSM KRYE LPAP SSGQ KNDI TAWQ ECVN NSMA QLEH QAVR IENL ELMS QHGC NAWK VYNE NLVH MIEH AQKE LQKL RKHI QDLN WQRK NMQL TAGS KLRE MESN WVSL VSKN YEIE RTIV QLEN EIYQ IKQQ HGEA NKEN IRQD F
Gene ID:10286
Uniprot:O75934
Cellular Location:Nucleus, nucleolus
Calculated MW:26kDa
Observed MW:25kDa
UniProt Protein Function:BCAS2: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Belongs to the SPF27 family.
UniProt Protein Details:

Protein type:Nucleolus; RNA splicing; Spliceosome; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: nucleoplasm; spliceosome; DNA replication factor A complex; nucleolus; nucleus; cell junction

Molecular Function:protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; RNA splicing; gene expression

UniProt Code:O75934
NCBI GenInfo Identifier:71153839
NCBI Gene ID:10286
NCBI Accession:O75934.1
UniProt Secondary Accession:O75934,Q6FGS0,
UniProt Related Accession:O75934
Molecular Weight:225
NCBI Full Name:Pre-mRNA-splicing factor SPF27
NCBI Synonym Full Names:breast carcinoma amplified sequence 2
NCBI Official Symbol:BCAS2  
NCBI Official Synonym Symbols:DAM1; SPF27; Snt309  
NCBI Protein Information:pre-mRNA-splicing factor SPF27; breast carcinoma-amplified sequence 2; spliceosome-associated protein SPF 27; DNA amplified in mammary carcinoma 1 protein; spliceosome associated protein, amplified in breast cancer
UniProt Protein Name:Pre-mRNA-splicing factor SPF27
UniProt Synonym Protein Names:Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; Spliceosome-associated protein SPF 27
UniProt Gene Name:BCAS2  
UniProt Entry Name:SPF27_HUMAN

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