Anti-BATF3 Antibody (CAB14906)
- SKU:
- CAB14906
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-BATF3 Antibody |
| Antibody SKU: | CAB14906 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human BATF3 (NP_061134.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Rat |
| Positive Samples: | Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human BATF3 (NP_061134.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSQG LPAA GSVL QRSV AAPG NQPQ PQPQ QQSP EDDD RKVR RREK NRVA AQRS RKKQ TQKA DKLH EEYE SLEQ ENTM LRRE IGKL TEEL KHLT EALK EHEK MCPL LLCP MNFV PVPP RPDP VAGC LPR |
| Gene ID: | 55509 |
| Uniprot: | Q9NR55 |
| Cellular Location: | Nucleus |
| Calculated MW: | 14kDa |
| Observed MW: | 14kDa |
| Synonyms: | BATF3, JDP1, JUNDM1, SNFT |
| Background: | This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription. |
| UniProt Protein Function: | BATF3: Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12- O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities. Belongs to the bZIP family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 1q32.3 Cellular Component: nucleus Molecular Function:protein binding; transcription corepressor activity; transcription factor activity Biological Process: myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; response to virus; transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009] |
| UniProt Code: | Q9NR55 |
| NCBI GenInfo Identifier: | 74752916 |
| NCBI Gene ID: | 55509 |
| NCBI Accession: | Q9NR55.1 |
| UniProt Secondary Accession: | Q9NR55,Q9D275, P97876, |
| UniProt Related Accession: | Q9NR55 |
| Molecular Weight: | 14,468 Da |
| NCBI Full Name: | Basic leucine zipper transcriptional factor ATF-like 3 |
| NCBI Synonym Full Names: | basic leucine zipper ATF-like transcription factor 3 |
| NCBI Official Symbol: | BATF3 |
| NCBI Official Synonym Symbols: | JDP1; SNFT; JUNDM1 |
| NCBI Protein Information: | basic leucine zipper transcriptional factor ATF-like 3 |
| UniProt Protein Name: | Basic leucine zipper transcriptional factor ATF-like 3 |
| UniProt Synonym Protein Names: | 21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT |
| Protein Family: | Basic leucine zipper transcriptional factor |
| UniProt Gene Name: | BATF3 |
| UniProt Entry Name: | BATF3_HUMAN |
 | Western blot analysis of extracts of rat spleen, using BATF3 antibody (CAB14906) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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