Anti-AVEN Antibody (CAB12910)
- SKU:
- CAB12910
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-AVEN Antibody |
| Antibody SKU: | CAB12910 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 203-362 of human AVEN (NP_065104.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:1000 - 1:3000 IF 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | 22RV1, HT-29, LO2, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 203-362 of human AVEN (NP_065104.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VQGT VPLE VPQV KPKR TDDG KGLG MQLK GPLG PGGR GPIF ELKS VAAG CPVL LGKD NPSP GPSR DSQK PTSP LQSA GDHL EEEL DLLL NLDA PIKE GDNI LPDQ TSQD LKSK EDGE VVQE EEVC AKPS VTEE KNME PEQP STSK NVTE EELE DWLD SMIS |
| Gene ID: | 57099 |
| Uniprot: | Q9NQS1 |
| Cellular Location: | Endomembrane system, Peripheral membrane protein |
| Calculated MW: | 38kDa |
| Observed MW: | 55kDa |
| Synonyms: | AVEN, PDCD12 |
| Background: |
| UniProt Protein Function: | AVEN: Protects against apoptosis mediated by Apaf-1. Binds Apaf-1, BCL-2 and BAD (Bcl-xl). Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas. |
| UniProt Protein Details: | Protein type:Inhibitor; Apoptosis Chromosomal Location of Human Ortholog: 15q13.1 Cellular Component: membrane; endomembrane system; intracellular Molecular Function:protein binding Biological Process: apoptosis; negative regulation of apoptosis |
| UniProt Code: | Q9NQS1 |
| NCBI GenInfo Identifier: | 9966841 |
| NCBI Gene ID: | 57099 |
| NCBI Accession: | NP_065104.1 |
| UniProt Related Accession: | Q9NQS1 |
| Molecular Weight: | 38,506 Da |
| NCBI Full Name: | cell death regulator Aven |
| NCBI Synonym Full Names: | apoptosis, caspase activation inhibitor |
| NCBI Official Symbol: | AVEN |
| NCBI Official Synonym Symbols: | PDCD12 |
| NCBI Protein Information: | cell death regulator Aven; programmed cell death 12 |
| UniProt Protein Name: | Cell death regulator Aven |
| Protein Family: | Avenin |
| UniProt Gene Name: | AVEN |
| UniProt Entry Name: | AVEN_HUMAN |
 | Western blot analysis of extracts of various cell lines, using AVEN antibody (CAB12910) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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