Anti-ATP8B3 Antibody (CAB17834)
- SKU:
- CAB17834
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-ATP8B3 Antibody |
| Antibody SKU: | CAB17834 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human ATP8B3 (NP_620168.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HCT116 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human ATP8B3 (NP_620168.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VTAA RNFG YVFL SRTQ DTVT IMEL GEER VYQV LAIM DFNS TRKR MSVL VRKP EGAI CLYT KGAD TVIF ERLH RRGA MEFA TEEA LAAF AQET LRTL CLAY REVA EDIY EDWQ QRHQ EASL LLQN RAQA LQQL LGAT AIED RLQD GVPE TIKC LKKS NIKI WVLT GDKQ ETAV NIGF ACEL LSEN MLIL EEKE ISRI LETY WENS NNLL TRES LSQV KLAL VING DFLD KLLV SLRK EPRA LAQN VNMD EAWQ ELGQ SRRD FLYA RRLS LLCR RFGL PLAA PPAQ DSRA RRSS EVLQ ERAF V |
| Gene ID: | 148229 |
| Uniprot: | O60423 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 147kDa |
 | Western blot - ATP8B3 Rabbit pAb (CAB17834) |
| Synonyms: | ATPIK, ATP8B3 |
| Background: | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to the other. This gene encodes member 3 of phospholipid-transporting ATPase 8B; other members of this protein family are located on chromosomes 1, 15 and 18. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| UniProt Protein Function: | ATP8B3: belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to the other. This gene encodes member 3 of phospholipid-transporting ATPase 8B; other members of this protein family are located on chromosomes 1, 15 and 18. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| UniProt Protein Details: | Protein type:Hydrolase; Transporter; Membrane protein, integral; EC 3.6.3.1; Membrane protein, multi-pass; Transporter, ion channel Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: Golgi apparatus; endoplasmic reticulum; plasma membrane; integral to membrane; acrosomal membrane Molecular Function:phospholipid-translocating ATPase activity; magnesium ion binding; ATP binding Biological Process: phospholipid translocation; metabolic process; binding of sperm to zona pellucida; Golgi organization and biogenesis |
| NCBI Summary: | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to the other. This gene encodes member 3 of phospholipid-transporting ATPase 8B; other members of this protein family are located on chromosomes 1, 15 and 18. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| UniProt Code: | O60423 |
| NCBI GenInfo Identifier: | 295821170 |
| NCBI Gene ID: | 148229 |
| NCBI Accession: | NP_001171473.1 |
| UniProt Secondary Accession: | O60423,Q7Z485, Q8IVB8, Q8N4Y8, Q96M22, |
| UniProt Related Accession: | O60423 |
| Molecular Weight: | 146,752 Da |
| NCBI Full Name: | phospholipid-transporting ATPase IK isoform 2 |
| NCBI Synonym Full Names: | ATPase, aminophospholipid transporter, class I, type 8B, member 3 |
| NCBI Official Symbol: | ATP8B3 |
| NCBI Official Synonym Symbols: | ATPIK |
| NCBI Protein Information: | phospholipid-transporting ATPase IK; ATPase, class I, type 8B, member 3; aminophospholipid translocase ATP8B3; probable phospholipid-transporting ATPase IK; potential phospholipid-transporting ATPase IK |
| UniProt Protein Name: | Phospholipid-transporting ATPase IK |
| UniProt Synonym Protein Names: | ATPase class I type 8B member 3 |
| Protein Family: | Phospholipid-transporting ATPase |
| UniProt Gene Name: | ATP8B3 |
| UniProt Entry Name: | AT8B3_HUMAN |
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