Anti-ATP23 Antibody (CAB12885)
- SKU:
- CAB12885
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Antibody Name: | Anti-ATP23 Antibody |
Antibody SKU: | CAB12885 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1). |
Application: | WB |
Recommended Dilution: | WB 1:1000 - 1:3000 |
Reactivity: | Mouse, Rat |
Positive Samples: | Mouse brain, Rat brain |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MAGA PDER RRGP AAGE QLQQ QHVS CQVF PERL AQGN PQQG FFSS FFTS NQKC QLRL LKTL ETNP YVKL LLDA MKHS GCAV NKDR HFSC EDCN GNVS GGFD ASTS QIVL CQNN IHNQ AHMN RVVT HELI HAFD HCRA HVDW FTNI RHLA CSEV RAAN LSGD CSLV NEIF RLHF GLKQ HHQT CVRD RATL SILA VRNI SKEV AKKA VDEV FESC FNDH EPFG RIPH NKTY ARYA HRDF ENRD RYYS NI |
Gene ID: | 91419 |
Uniprot: | Q9Y6H3 |
Cellular Location: | |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
Synonyms: | ATP23, KUB3, XRCC6BP1 |
Background: | The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | XRCC6BP1: Belongs to the peptidase M76 family. |
UniProt Protein Details: | Protein type:DNA repair, damage; EC 3.4.24.-; Protease Chromosomal Location of Human Ortholog: 12q14.1 Cellular Component: intracellular membrane-bound organelle; plasma membrane Molecular Function:DNA-dependent protein kinase activity Biological Process: double-strand break repair via nonhomologous end joining |
NCBI Summary: | The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016] |
UniProt Code: | Q9Y6H3 |
NCBI GenInfo Identifier: | 224471894 |
NCBI Gene ID: | 91419 |
NCBI Accession: | Q9Y6H3.3 |
UniProt Secondary Accession: | Q9Y6H3,Q1RLM4, Q96E81, |
UniProt Related Accession: | Q9Y6H3 |
Molecular Weight: | 28kDa |
NCBI Full Name: | Mitochondrial inner membrane protease ATP23 homolog |
NCBI Synonym Full Names: | ATP23 metallopeptidase and ATP synthase assembly factor homolog |
NCBI Official Symbol: | ATP23 |
NCBI Official Synonym Symbols: | KUB3; XRCC6BP1 |
NCBI Protein Information: | mitochondrial inner membrane protease ATP23 homolog |
UniProt Protein Name: | Mitochondrial inner membrane protease ATP23 homolog |
UniProt Synonym Protein Names: | Ku70-binding protein 3; XRCC6-binding protein 1 |
Protein Family: | Mitochondrial inner membrane protease |
UniProt Gene Name: | ATP23 |