Anti-ATP10A Antibody (CAB15873)
- SKU:
- CAB15873
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-ATP10A Antibody |
| Antibody SKU: | CAB15873 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-690 of human ATP10A (NP_077816.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | A-549, U-251MG, DU-145, OVCAR3, HT-29, A-431 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-690 of human ATP10A (NP_077816.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RRCT VSGV EYSH DANA QRLA RYQE ADSE EEEV VPRG GSVS QRGS IGSH QSVR VVHR TQST KSHR RTGS RAEA KRAS MLSK HTAF SSPM EKDI TPDP KLLE KVSE CDKS LAVA RHQE HLLA HLSP ELSD VFDF FIAL TICN TVVV TSPD QPRT KVRV RFEL KSPV KTIE DFLR RFTP SCLT SGCS SIGS LAAN KSSH KLGS SFPS TPSS DGML LRLE ERLG QPTS AIAS NGYS SQAD NWAS ELAQ EQES ERE |
| Gene ID: | 57194 |
| Uniprot: | O60312 |
| Cellular Location: | Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein |
| Calculated MW: | 17kDa/167kDa |
| Observed MW: | 170kDa |
| Synonyms: | ATP10A, ATP10C, ATPVA, ATPVC |
| Background: | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene is maternally expressed. It maps within the most common interval of deletion responsible for Angelman syndrome, also known as 'happy puppet syndrome'. |
| UniProt Code: | O60312 |
| NCBI GenInfo Identifier: | 14424433 |
| NCBI Gene ID: | 57194 |
| NCBI Accession: | NP_077816.1 |
| UniProt Secondary Accession: | O60312,Q969I4, |
| UniProt Related Accession: | O60312 |
| Molecular Weight: | 167,688 Da |
| NCBI Full Name: | probable phospholipid-transporting ATPase VA |
| NCBI Synonym Full Names: | ATPase, class V, type 10A |
| NCBI Official Symbol: | ATP10A |
| NCBI Official Synonym Symbols: | ATPVA; ATPVC; ATP10C |
| NCBI Protein Information: | probable phospholipid-transporting ATPase VA; ATPase, Class V, type 10C; aminophospholipid translocase VA; P4-ATPase flippase complex alpha subunit ATP10A; ATPase type IV, phospholipid transporting (P-type) |
| UniProt Protein Name: | Probable phospholipid-transporting ATPase VA |
| UniProt Synonym Protein Names: | ATPase class V type 10A; Aminophospholipid translocase VA; P4-ATPase flippase complex alpha subunit ATP10A |
| Protein Family: | Probable phospholipid-transporting ATPase |
| UniProt Gene Name: | ATP10A |
| UniProt Entry Name: | AT10A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ATP10A antibody (CAB15873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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