Anti-ASMT Antibody (CAB6529)
- SKU:
- CAB6529
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-ASMT Antibody |
| Antibody SKU: | CAB6529 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human ASMT (NP_001164510.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human ASMT (NP_001164510.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGSS EDQA YRLL NDYA NGFM VSQV LFAA CELG VFDL LAEA PGPL DVAA VAAG VRAS AHGT ELLL DICV SLKL LKVE TRGG KAFY RNTE LSSD YLTT VSPT SQCS MLKY MGRT SYRC WGHL ADAV REGR NQYL ETFG VPAE ELFT AIYR SEGE RLQF MQAL QEVW SVNG RSVL TAFD LSVF PLMC DLGG DFFK DPLP EADL YILA RVLH DWAD GKCS HLLE RIYH TCKP GGGI LVIE SLLD EDRR GPLL TQLY SLNM LVQT EGQE RTPT HYHM LLSS AGFR DFQF KKTG AIYD AILA RK |
| Gene ID: | 438 |
| Uniprot: | P46597 |
| Cellular Location: | |
| Calculated MW: | 33kDa/38kDa/41kDa |
| Observed MW: | Refer to figures |
| Synonyms: | ASMT, ASMTY, HIOMT, HIOMTY |
| Background: | This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. |
| UniProt Protein Function: | ASMT: Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin. Belongs to the methyltransferase superfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Amino Acid Metabolism - tryptophan; EC 2.1.1.4; Methyltransferase Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.2 Cellular Component: cytosol Molecular Function:acetylserotonin O-methyltransferase activity; identical protein binding; O-methyltransferase activity; protein homodimerization activity; S-methyltransferase activity Biological Process: indolalkylamine biosynthetic process; melatonin biosynthetic process; translation |
| NCBI Summary: | This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010] |
| UniProt Code: | P46597 |
| NCBI GenInfo Identifier: | 1170276 |
| NCBI Gene ID: | 438 |
| NCBI Accession: | P46597.1 |
| UniProt Secondary Accession: | P46597,Q16598, Q5JQ72, Q5JQ73, B2RC33, |
| UniProt Related Accession: | P46597 |
| Molecular Weight: | Calculated MW: 33kDa/38kDa/41kDaObserved MW: 52kDa |
| NCBI Full Name: | Acetylserotonin O-methyltransferase |
| NCBI Synonym Full Names: | acetylserotonin O-methyltransferase |
| NCBI Official Symbol: | ASMT |
| NCBI Official Synonym Symbols: | ASMTY; HIOMT; HIOMTY |
| NCBI Protein Information: | acetylserotonin O-methyltransferase |
| UniProt Protein Name: | Acetylserotonin O-methyltransferase |
| UniProt Synonym Protein Names: | Hydroxyindole O-methyltransferase; HIOMT |
| Protein Family: | Acetylserotonin O-methyltransferase |
| UniProt Gene Name: | ASMT |
 | Immunofluorescence analysis of MCF7 cells using ASMT antibody (CAB6529). |
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