Anti-ASB4 Antibody (CAB17159)
- SKU:
- CAB17159
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-ASB4 Antibody |
| Antibody SKU: | CAB17159 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ASB4 (NP_665879.1). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ASB4 (NP_665879.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDGT TAPV TKSG AAKL VKRN FLEA LKSN DFGK LKAI LIQR QIDV DTVF EVED ENMV LASY KQGY WLPS YKLK SSWA TGLH LSVL FGHV ECLL VLLD HNAT INCR PNGK TPLH VACE MANV DCVK ILCD RGAK LNCY SLSG HTAL HFCT TPSS ILCA KQLV WRGA NVNM KTNN QDEE TPLH TAAH FGLS ELVA FYVE HGAI VDSV NAHM ETPL AIAA YWAL RFKE QEYS TEHH LVCR MLLD YKAE VNAR DDDF KSPL HKAA WNCD HVLM HMML EAGA EANL MDIN GCAA IQYV LKVT SVRP |
| Gene ID: | 51666 |
| Uniprot: | Q9Y574 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
 | Immunohistochemistry - ASB4 Polyclonal Antibody (CAB17159) |
| Synonyms: | ASB4, ASB-4 |
| Background: | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known. |
| UniProt Protein Function: | ASB4: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 7q21-q22 Cellular Component: Cul2-RING ubiquitin ligase complex; Cul5-RING ubiquitin ligase complex |
| NCBI Summary: | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y574 |
| NCBI GenInfo Identifier: | 20532003 |
| NCBI Gene ID: | 51666 |
| NCBI Accession: | Q9Y574.1 |
| UniProt Secondary Accession: | Q9Y574,O14586, Q14D68, Q8TBT2, A4D1H6, |
| UniProt Related Accession: | Q9Y574 |
| Molecular Weight: | 38,931 Da |
| NCBI Full Name: | Ankyrin repeat and SOCS box protein 4 |
| NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 4 |
| NCBI Official Symbol: | ASB4 |
| NCBI Official Synonym Symbols: | ASB-4 |
| NCBI Protein Information: | ankyrin repeat and SOCS box protein 4 |
| UniProt Protein Name: | Ankyrin repeat and SOCS box protein 4 |
| Protein Family: | Ankyrin repeat and SOCS box protein |
| UniProt Gene Name: | ASB4 |
| UniProt Entry Name: | ASB4_HUMAN |
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