Anti-ARL6IP1 Antibody (CAB17107)
- SKU:
- CAB17107
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-ARL6IP1 Antibody |
| Antibody SKU: | CAB17107 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL6IP1 (NP_055976.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL6IP1 (NP_055976.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAEG DNRS TNLL AAET ASLE EQLQ GWGE VMLM ADKV LRWE RAWF PPAI MGVV SLVF LIIY YLDP SVLS GVSC FVMF LCLA DYLV PILA PRIF GSNK WTTE |
| Gene ID: | 23204 |
| Uniprot: | Q15041 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | ARL6IP1, AIP1, ARL6IP, ARMER, SPG61 |
| Background: | This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | ARL6IP: May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Belongs to the ARL6ip family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 16p12-p11.2 Cellular Component: membrane; integral to membrane; translocon complex; cytosol Molecular Function:protein binding Biological Process: cotranslational protein targeting to membrane Disease: Spastic Paraplegia 61, Autosomal Recessive |
| NCBI Summary: | This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015] |
| UniProt Code: | Q15041 |
| NCBI GenInfo Identifier: | 14424435 |
| NCBI Gene ID: | 23204 |
| NCBI Accession: | Q15041.2 |
| UniProt Secondary Accession: | Q15041,B7Z6S5, B7Z791, F5GXP4, |
| UniProt Related Accession: | Q15041 |
| Molecular Weight: | 17,158 Da |
| NCBI Full Name: | ADP-ribosylation factor-like protein 6-interacting protein 1 |
| NCBI Synonym Full Names: | ADP-ribosylation factor-like 6 interacting protein 1 |
| NCBI Official Symbol: | ARL6IP1 |
| NCBI Official Synonym Symbols: | AIP1; ARMER; SPG61; ARL6IP |
| NCBI Protein Information: | ADP-ribosylation factor-like protein 6-interacting protein 1; aip-1; ARL-6-interacting protein 1; apoptotic regulator in the membrane of the endoplasmic reticulum |
| UniProt Protein Name: | ADP-ribosylation factor-like protein 6-interacting protein 1 |
| Protein Family: | ADP-ribosylation factor-like protein 6-interacting protein |
| UniProt Gene Name: | ARL6IP1 |
| UniProt Entry Name: | AR6P1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ARL6IP1 antibody (CAB17107) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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