Anti-ARHGEF10L Antibody (CAB17716)
- SKU:
- CAB17716
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-ARHGEF10L Antibody |
| Antibody SKU: | CAB17716 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1120-1230 of human ARHGEF10L (NP_001011722). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1120-1230 of human ARHGEF10L (NP_001011722). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SHVG RELT RKKG ILLQ YRLR STAH LPGP LLSM REPA PADG AALE HSEE DGSI YEMA DDPD IWVR SRPC ARDA HRKE ICSV AIIS GGQG YRNF GSAL GSSG RQAP CGET DST |
| Gene ID: | 55160 |
| Uniprot: | Q9HCE6 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 140kDa |
 | Western blot - ARHGEF10L Polyclonal Antibody (CAB17716) |
| Synonyms: | GrinchGEF, ARHGEF10L |
| Background: | This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2016] |
| UniProt Protein Function: | ARHGEF10L: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor; Cytoskeletal; GEFs; GEFs, Rac/Rho; Deacetylase Chromosomal Location of Human Ortholog: 1p36.13 Cellular Component: cytoplasm Molecular Function:Rho guanyl-nucleotide exchange factor activity |
| NCBI Summary: | ARHGEF10L is a member of the RhoGEF family of guanine nucleotide exchange factors (GEFs) that activate Rho GTPases (Winkler et al., 2005 [PubMed 16112081]).[supplied by OMIM, Dec 2008] |
| UniProt Code: | Q9HCE6 |
| NCBI GenInfo Identifier: | 74136547 |
| NCBI Gene ID: | 55160 |
| NCBI Accession: | NP_001011722.2 |
| UniProt Secondary Accession: | Q9HCE6,Q17RW1, Q3YFJ4, Q5VXI5, Q5VXI6, Q66K51, Q6P0L7 Q8NAV5, Q9NVT3, B7ZKS1, |
| UniProt Related Accession: | Q9HCE6 |
| Molecular Weight: | 140,409 Da |
| NCBI Full Name: | rho guanine nucleotide exchange factor 10-like protein isoform 2 |
| NCBI Synonym Full Names: | Rho guanine nucleotide exchange factor (GEF) 10-like |
| NCBI Official Symbol: | ARHGEF10L |
| NCBI Official Synonym Symbols: | GrinchGEF |
| NCBI Protein Information: | rho guanine nucleotide exchange factor 10-like protein |
| UniProt Protein Name: | Rho guanine nucleotide exchange factor 10-like protein |
| UniProt Synonym Protein Names: | GrinchGEF |
| Protein Family: | Rho guanine nucleotide exchange factor 10-like protein |
| UniProt Gene Name: | ARHGEF10L |
| UniProt Entry Name: | ARGAL_HUMAN |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
