Anti-ANXA13 Antibody (CAB13728)
- SKU:
- CAB13728
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-ANXA13 Antibody |
| Antibody SKU: | CAB13728 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human ANXA13 (NP_004297.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, Mouse small intestine, Mouse kidney, Rat small intestine |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human ANXA13 (NP_004297.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGNR HAKA SSPQ GFDV DRDA KKLN KACK GMGT NEAA IIEI LSGR TSDE RQQI KQKY KATY GKEL EEVL KSEL SGNF EKTA LALL DRPS EYAA RQLQ KAMK GLGT DESV LIEV LCTR TNKE IIAI KEAY QRLF DRSL ESDV KGDT SGNL KKIL VSLL QANR NEGD DVDK DLAG QDAK DLYD AGEG RWGT DELA FNEV LAKR SYKQ LRAT FQAY QILI GKDI EEAI EEET SGDL QKAY LTLV RCAQ DCED YFAE RLYK SMKG AGTD EETL IRIV VTRA EVDL QGIK AKFQ EKYQ KSLS DMVR SDTS GDFR KLLV ALLH |
| Gene ID: | 312 |
| Uniprot: | P27216 |
| Cellular Location: | Cell membrane |
| Calculated MW: | 35kDa/39kDa |
| Observed MW: | 36kDa |
| Synonyms: | ANXA13, ANX13, ISA |
| Background: | This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| UniProt Protein Function: | ANXA13: a calcium/phospholipid-binding protein associated with the cell membrane. ANXA13 is the probable common ancestor of the annexin family of proteins. Annexins all bind to phospholipids in a calcium-dependent manner. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion. |
| UniProt Protein Details: | Protein type:Calcium-binding; Lipid-binding Chromosomal Location of Human Ortholog: 8q24.13 Cellular Component: nucleoplasm; extracellular space; basolateral plasma membrane; apical plasma membrane; plasma membrane; lipid raft Molecular Function:calcium-dependent phospholipid binding; phosphatidylserine binding; phosphatidylcholine binding; calcium ion binding Biological Process: negative regulation of Golgi to plasma membrane protein transport; positive regulation of Golgi to plasma membrane protein transport; cell differentiation |
| NCBI Summary: | This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P27216 |
| NCBI GenInfo Identifier: | 281185504 |
| NCBI Gene ID: | 312 |
| NCBI Accession: | P27216.3 |
| UniProt Secondary Accession: | P27216,Q9BQR5, |
| UniProt Related Accession: | P27216 |
| Molecular Weight: | 39,744 Da |
| NCBI Full Name: | Annexin A13 |
| NCBI Synonym Full Names: | annexin A13 |
| NCBI Official Symbol: | ANXA13 |
| NCBI Official Synonym Symbols: | ISA; ANX13 |
| NCBI Protein Information: | annexin A13; annexin-13; annexin XIII; intestine-specific annexin; annexin, intestine-specific |
| UniProt Protein Name: | Annexin A13 |
| UniProt Synonym Protein Names: | Annexin XIII; Annexin-13; Intestine-specific annexin; ISA |
| Protein Family: | Annexin |
| UniProt Gene Name: | ANXA13 |
| UniProt Entry Name: | ANX13_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ANXA13 antibody (CAB13728) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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