Anti-ANP32A Antibody (CAB5768)
- SKU:
- CAB5768
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-ANP32A Antibody |
| Antibody SKU: | CAB5768 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_006296.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HepG2, HL-60, MCF7, Raji, U-251MG, Mouse brain, HT-29 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_006296.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEMG RRIH LELR NRTP SDVK ELVL DNSR SNEG KLEG LTDE FEEL EFLS TINV GLTS IANL PKLN KLKK LELS DNRV SGGL EVLA EKCP NLTH LNLS GNKI KDLS TIEP LKKL ENLK SLDL FNCE VTNL NDYR ENVF KLLP QLTY LDGY DRDD KEAP DSDA EGYV EGLD DE |
| Gene ID: | 8125 |
| Uniprot: | P39687 |
| Cellular Location: | Cytoplasm, Endoplasmic reticulum, Nucleus |
| Calculated MW: | 28kDa |
| Observed MW: | 28kDa |
| Synonyms: | ANP32A, C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32 |
| Background: |
| UniProt Protein Function: | ANP32A: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1- mediated transcriptional repression. Belongs to the ANP32 family. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 15q23 Cellular Component: nucleoplasm; endoplasmic reticulum; perinuclear region of cytoplasm; cytoplasm; nucleus Molecular Function:protein binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; nucleocytoplasmic transport; gene expression |
| UniProt Code: | P39687 |
| NCBI GenInfo Identifier: | 730318 |
| NCBI Gene ID: | 8125 |
| NCBI Accession: | P39687.1 |
| UniProt Secondary Accession: | P39687,Q53FK4, Q5J8L8, Q7M4N6, B2R6T4, |
| UniProt Related Accession: | P39687 |
| Molecular Weight: | 28,585 Da |
| NCBI Full Name: | Acidic leucine-rich nuclear phosphoprotein 32 family member A |
| NCBI Synonym Full Names: | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| NCBI Official Symbol: | ANP32A |
| NCBI Official Synonym Symbols: | LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1 |
| NCBI Protein Information: | acidic leucine-rich nuclear phosphoprotein 32 family member A; mapmodulin; hepatopoietin Cn; acidic nuclear phosphoprotein pp32; leucine-rich acidic nuclear protein; putative HLA-DR-associated protein I; inhibitor-1 of protein phosphatase-2A; cerebellar leucine rich acidic nuclear protein; putative human HLA class II associated protein I; potent heat-stable protein phosphatase 2A inhibitor I1PP2A |
| UniProt Protein Name: | Acidic leucine-rich nuclear phosphoprotein 32 family member A |
| UniProt Synonym Protein Names: | Acidic nuclear phosphoprotein pp32; pp32; Leucine-rich acidic nuclear protein; LANP; Mapmodulin; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Putative HLA-DR-associated protein I; PHAPI |
| Protein Family: | Acidic leucine-rich nuclear phosphoprotein 32 family |
| UniProt Gene Name: | ANP32A |
| UniProt Entry Name: | AN32A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ANP32A antibody (CAB5768) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using ANP32A Antibody (CAB5768) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human breast cancer using ANP32A Antibody (CAB5768) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse brain using ANP32A Antibody (CAB5768) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of A549 cells using ANP32A antibody (CAB5768). Blue: DAPI for nuclear staining. |
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