Anti-AMBP Antibody (MACO0546)
- SKU:
- MACO0546
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG3
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Monoclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Product Name: | Anti-AMBP Antibody |
Product Sku: | MACO0546 |
Size: | 50ug |
Host Species: | Mouse |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | IHC:1:50-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human protein AMBP |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%,Protein G purified |
Clonality: | Monoclonal |
Isotype: | IgG3 |
Conjugate: | Non-conjugated |
Background: | Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization. Trypstatin is a trypsin inhibitor |
Synonyms: | Protein HC,Alpha-1 microglycoprotein,ITI-LC,Bikunin,EDC1,HI-30 |
Immunohistochemical of paraffin-embedded human liver tissue using MACO0546 at dilution of 1:200 |
UniProt Protein Function: | AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 9q32-q33 Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; plasma membrane; extracellular region Molecular Function:serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; calcium oxalate binding; IgA binding; heme binding; calcium channel inhibitor activity Biological Process: negative regulation of JNK cascade; receptor-mediated endocytosis; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage |
NCBI Summary: | This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008] |
UniProt Code: | P02760 |
NCBI GenInfo Identifier: | 122801 |
NCBI Gene ID: | 259 |
NCBI Accession: | P02760.1 |
UniProt Related Accession: | P02760 |
Molecular Weight: | |
NCBI Full Name: | Protein AMBP |
NCBI Synonym Full Names: | alpha-1-microglobulin/bikunin precursor |
NCBI Official Symbol: | AMBPÂ Â |
NCBI Official Synonym Symbols: | A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILCÂ Â |
NCBI Protein Information: | protein AMBP |
UniProt Protein Name: | Protein AMBP |
UniProt Synonym Protein Names: | Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge |
Protein Family: | Alpha-1-macroglobulin |
UniProt Gene Name: | AMBPÂ Â |
UniProt Entry Name: | AMBP_HUMAN |