Anti-ALOX12 Antibody (CAB14703)
- SKU:
- CAB14703
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
Antibody Name: | Anti-ALOX12 Antibody |
Antibody SKU: | CAB14703 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | IHC IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 483-663 of human ALOX12 (NP_000688.2). |
Application: | IHC IF |
Recommended Dilution: | IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 483-663 of human ALOX12 (NP_000688.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | YQRD DIVK GDPE LQAW CREI TEVG LCQA QDRG FPVS FQSQ SQLC HFLT MCVF TCTA QHAA INQG QLDW YAWV PNAP CTMR MPPP TTKE DVTM ATVM GSLP DVRQ ACLQ MAIS WHLS RRQP DMVP LGHH KEKY FSGP KPKA VLNQ FRTD LEKL EKEI TARN EQLD WPYE YLKP SCIE NSVT I |
Gene ID: | 239 |
Uniprot: | P18054 |
Cellular Location: | Cytoplasm, Membrane, cytosol |
Calculated MW: | 75kDa |
Observed MW: |
Synonyms: | ALOX12, 12-LOX, 12S-LOX, LOG12, 12S-type |
Background: |
UniProt Protein Function: | ALOX12: Oxygenase and 14,15-leukotriene A4 synthase activity. Belongs to the lipoxygenase family. |
UniProt Protein Details: | Protein type:EC 1.13.11.31; Lipid Metabolism - arachidonic acid; Oxidoreductase; Apoptosis Chromosomal Location of Human Ortholog: 17p13.1 Cellular Component: cytoplasm; cytosol; membrane; sarcolemma Molecular Function:arachidonate 12-lipoxygenase activity; hepoxilin A3 synthase activity; hepoxilin-epoxide hydrolase activity; lipoxygenase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; protein binding Biological Process: arachidonic acid metabolic process; cell motility; fatty acid oxidation; hepoxilin biosynthetic process; hepoxilin metabolic process; linoleic acid metabolic process; lipoxygenase pathway; negative regulation of apoptosis; positive regulation of angiogenesis; positive regulation of cell adhesion; positive regulation of cell growth; positive regulation of cell migration; positive regulation of cell proliferation |
UniProt Code: | P18054 |
NCBI GenInfo Identifier: | 125987838 |
NCBI Gene ID: | 239 |
NCBI Accession: | P18054.4 |
UniProt Secondary Accession: | P18054,O95569, Q6ISF8, Q9UQM4, |
UniProt Related Accession: | P18054 |
Molecular Weight: | 75,694 Da |
NCBI Full Name: | Arachidonate 12-lipoxygenase, 12S-type |
NCBI Synonym Full Names: | arachidonate 12-lipoxygenase, 12S type |
NCBI Official Symbol: | ALOX12 |
NCBI Official Synonym Symbols: | LOG12; 12-LOX; 12S-LOX |
NCBI Protein Information: | arachidonate 12-lipoxygenase, 12S-type |
UniProt Protein Name: | Arachidonate 12-lipoxygenase, 12S-type |
UniProt Synonym Protein Names: | Lipoxin synthase 12-LO (EC:3.3.2.-); Platelet-type lipoxygenase 12 |
Protein Family: | Arachidonate 12-lipoxygenase |
UniProt Gene Name: | ALOX12 |
UniProt Entry Name: | LOX12_HUMAN |