Anti-ALG13 Antibody (CAB18115)
- SKU:
- CAB18115
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Antibody Name: | Anti-ALG13 Antibody |
Antibody SKU: | CAB18115 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human ALG13. |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | Raji, K-562, Jurkat, HepG2, Mouse liver, Mouse kidney |
Immunogen: | Recombinant protein of human ALG13. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 79868 |
Uniprot: | Q9NP73 |
Cellular Location: | |
Calculated MW: | 18kDa/106kDa/117kDa/126kDa |
Observed MW: | 126kDa |
Synonyms: | CDG1S, CXorf45, EIEE36, GLT28D1, MDS031, TDRD13, YGL047W, ALG13 |
Background: | The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | ALG13: Isoform 2 may be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway. Belongs to the glycosyltransferase 28 family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.19.12; Transferase; EC 2.4.1.141; Glycan Metabolism - N-glycan biosynthesis Chromosomal Location of Human Ortholog: Xq23 Cellular Component: endoplasmic reticulum membrane Molecular Function:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Biological Process: dolichol-linked oligosaccharide biosynthetic process Disease: Congenital Disorder Of Glycosylation, Type Is |
NCBI Summary: | The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
UniProt Code: | Q9NP73 |
NCBI GenInfo Identifier: | 298286785 |
NCBI Gene ID: | 79868 |
NCBI Accession: | Q9NP73.2 |
UniProt Secondary Accession: | Q9NP73,Q17RC3, Q5JXY9, B1AKD6, B1AKM1, B2R5L5, B7Z6J0 B7Z804, B7Z847, B7Z9A8, B7ZAJ1, B7ZB57, |
UniProt Related Accession: | Q9NP73 |
Molecular Weight: | 106,858 Da |
NCBI Full Name: | Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 |
NCBI Synonym Full Names: | ALG13, UDP-N-acetylglucosaminyltransferase subunit |
NCBI Official Symbol: | ALG13 |
NCBI Official Synonym Symbols: | CDG1S; EIEE36; MDS031; TDRD13; CXorf45; GLT28D1; YGL047W |
NCBI Protein Information: | putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 |
UniProt Protein Name: | Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 |
UniProt Synonym Protein Names: | Asparagine-linked glycosylation 13 homolog; Glycosyltransferase 28 domain-containing protein 1; UDP-N-acetylglucosamine transferase subunit ALG13 homolog |
Protein Family: | UDP-N-acetylglucosamine transferase |
UniProt Gene Name: | ALG13 |
UniProt Entry Name: | ALG13_HUMAN |