Anti-ALDH9A1 Antibody (CAB7875)

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SKU:
CAB7875
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Frequently bought together:

Description

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Antibody Name:Anti-ALDH9A1 Antibody
Antibody SKU:CAB7875
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human ALDH9A1
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, 22Rv1, NCI-H460, Mouse liver, Mouse kidney, Rat liver, Rat kidney
Immunogen:A synthetic peptide of human ALDH9A1
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:223
Uniprot:P49189
Cellular Location:Cytoplasm
Calculated MW:46kDa/53kDa
Observed MW:54kDa
Synonyms:ALDH9A1, ALDH4, ALDH7, ALDH9, E3, TMABADH
Background:This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits.
UniProt Protein Function:ALDH9A1: Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Belongs to the aldehyde dehydrogenase family.
UniProt Protein Details:

Protein type:Other Amino Acids Metabolism - beta-alanine; Lipid Metabolism - fatty acid; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - ascorbate and aldarate; Oxidoreductase; Amino Acid Metabolism - tryptophan; EC 1.2.1.47; EC 1.2.1.3; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - butanoate; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - propanoate; Mitochondrial; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pyruvate

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: cytoplasm; cytosol

Molecular Function:3-chloroallyl aldehyde dehydrogenase activity; 4-trimethylammoniobutyraldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aminobutyraldehyde dehydrogenase activity

Biological Process: aldehyde metabolic process; carnitine biosynthetic process; hormone metabolic process; neurotransmitter biosynthetic process

NCBI Summary:This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]
UniProt Code:P49189
NCBI GenInfo Identifier:62511242
NCBI Gene ID:223
NCBI Accession:P49189.3
UniProt Secondary Accession:P49189,Q5VV90, Q6LCL1, Q9NZT7, B2R6X1, B4DXY7,
UniProt Related Accession:P49189
Molecular Weight:46,455 Da
NCBI Full Name:4-trimethylaminobutyraldehyde dehydrogenase
NCBI Synonym Full Names:aldehyde dehydrogenase 9 family member A1
NCBI Official Symbol:ALDH9A1  
NCBI Official Synonym Symbols:E3; ALDH4; ALDH7; ALDH9; TMABADH  
NCBI Protein Information:4-trimethylaminobutyraldehyde dehydrogenase
UniProt Protein Name:4-trimethylaminobutyraldehyde dehydrogenase
UniProt Synonym Protein Names:Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1 (EC:1.2.1.3); Gamma-aminobutyraldehyde dehydrogenase (EC:1.2.1.19); R-aminobutyraldehyde dehydrogenase
Protein Family:Aldehyde dehydrogenase family
UniProt Gene Name:ALDH9A1  
UniProt Entry Name:AL9A1_HUMAN
Anti-ALDH9A1 Antibody (CAB7875)Western blot analysis of extracts of various cell lines, using ALDH9A1 antibody (CAB7875) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-ALDH9A1 Antibody (CAB7875)Immunohistochemistry of paraffin-embedded rat heart using ALDH9A1 antibody (CAB7875) (40x lens).

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