| UniProt Protein Function: | ALDH1B1: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. Belongs to the aldehyde dehydrogenase family. |
| UniProt Protein Details: | Protein type:Oxidoreductase; Lipid Metabolism - fatty acid; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - lysine degradation; Mitochondrial; Other Amino Acids Metabolism - beta-alanine; EC 1.2.1.3; Secondary Metabolites Metabolism - limonene and pinene degradation; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - ascorbate and aldarate; Carbohydrate Metabolism - propanoate Chromosomal Location of Human Ortholog: 9p11.1 Cellular Component: nucleoplasm; mitochondrion; intracellular membrane-bound organelle; mitochondrial matrix Molecular Function:aldehyde dehydrogenase (NAD) activity Biological Process: ethanol catabolic process; carbohydrate metabolic process |
| NCBI Summary: | This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P30837 |
| NCBI GenInfo Identifier: | 311033472 |
| NCBI Gene ID: | 219 |
| NCBI Accession: | P30837.3 |
| UniProt Secondary Accession: | P30837,Q8WX76, Q9BV45, B2R8F0, |
| UniProt Related Accession: | P30837 |
| Molecular Weight: | 517 |
| NCBI Full Name: | Aldehyde dehydrogenase X, mitochondrial |
| NCBI Synonym Full Names: | aldehyde dehydrogenase 1 family, member B1 |
| NCBI Official Symbol: | ALDH1B1 |
| NCBI Official Synonym Symbols: | ALDH5; ALDHX |
| NCBI Protein Information: | aldehyde dehydrogenase X, mitochondrial; ALDH class 2; aldehyde dehydrogenase 5; acetaldehyde dehydrogenase 5 |
| UniProt Protein Name: | Aldehyde dehydrogenase X, mitochondrial |
| UniProt Synonym Protein Names: | Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1 |
| Protein Family: | Aldehyde dehydrogenase |
| UniProt Gene Name: | ALDH1B1 |
| UniProt Entry Name: | AL1B1_HUMAN |
