Anti-Adenylate kinase 4 Antibody (CAB2383)

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주문
SKU:
CAB2383
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
AK4
Synonyms:
AK 4
Synonyms:
AK3
Synonyms:
AK3L1
Synonyms:
AK3L2
Synonyms:
adenylate kinase 4
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Description

Product Name:Adenylate kinase 4 Rabbit mAb
Product Code:CAB2383
Size:20uL, 50uL, 100uL
Synonyms:AK4, AK 4, AK3, AK3L1, AK3L2, adenylate kinase 4
Applications:WB, IHC, IF
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Adenylate kinase 4.
Applications:WB, IHC, IF
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Rat
Positive Samples:293T, HeLa, SH-SY5Y
Immunogen:A synthesized peptide derived from human Adenylate kinase 4.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:205
Uniprot:P27144
Cellular Location:Mitochondrion matrix
Calculated MW:25kDa
Observed MW:27kDa
UniProt Protein Function:AK3L1: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP. Belongs to the adenylate kinase family.
UniProt Protein Details:

Protein type:Nucleotide Metabolism - purine; EC 2.7.4.10; EC 2.7.4.6; Mitochondrial; Kinase, other

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function:GTP binding; nucleoside diphosphate kinase activity; adenylate kinase activity; nucleoside triphosphate adenylate kinase activity; ATP binding

Biological Process: response to drug; ATP metabolic process; nucleoside triphosphate biosynthetic process; nucleoside diphosphate phosphorylation; ADP biosynthetic process; brain development; liver development; AMP metabolic process; GTP metabolic process

NCBI Summary:This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008]
UniProt Code:P27144
NCBI GenInfo Identifier:125157
NCBI Gene ID:205
NCBI Accession:P27144.1
UniProt Related Accession:P27144
Molecular Weight:~ 25kDa
NCBI Full Name:Adenylate kinase 4, mitochondrial
NCBI Synonym Full Names:adenylate kinase 4
NCBI Official Symbol:AK4  
NCBI Official Synonym Symbols:AK3; AK 4; AK3L1; AK3L2  
NCBI Protein Information:adenylate kinase 4, mitochondrial
UniProt Protein Name:Adenylate kinase 4, mitochondrial
UniProt Synonym Protein Names:Adenylate kinase 3-like; GTP:AMP phosphotransferase AK4
UniProt Gene Name:AK4  
UniProt Entry Name:KAD4_HUMAN
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