Anti-ACOX3 Antibody (CAB17020)
- SKU:
- CAB17020
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-ACOX3 Antibody |
| Antibody SKU: | CAB17020 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-100 of human ACOX3 (NP_001095137). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-100 of human ACOX3 (NP_001095137). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TALL PEFP RGPL DAYR ARAS FSWK ELAL FTEG EGML RFKK TIFS ALEN DPLF ARSP GADL SLEK YREL NFLR CKRI FEYD FLSV EDMF KSP |
| Gene ID: | 8310 |
| Uniprot: | O15254 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
 | Immunofluorescence - ACOX3 Rabbit pAb (CAB17020) |
| Synonyms: | ACOX3 |
| Background: | Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. |
| UniProt Protein Function: | ACOX3: Oxidizes the CoA-esters of 2-methyl-branched fatty acids. Belongs to the acyl-CoA oxidase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 1.3.3.6; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - fatty acid; Lipid Metabolism - unsaturated fatty acid biosynthesis; Oxidoreductase Chromosomal Location of Human Ortholog: 4p16.1 Cellular Component: membrane; peroxisomal matrix; peroxisome Molecular Function:acyl-CoA binding; acyl-CoA dehydrogenase activity; electron carrier activity; FAD binding; pristanoyl-CoA oxidase activity; receptor binding Biological Process: fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid beta-oxidation using acyl-CoA oxidase; lipid homeostasis |
| NCBI Summary: | Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O15254 |
| NCBI GenInfo Identifier: | 156104864 |
| NCBI Gene ID: | 8310 |
| NCBI Accession: | NP_003492.2 |
| UniProt Secondary Accession: | O15254,Q96AJ8, |
| UniProt Related Accession: | O15254 |
| Molecular Weight: | 69,575 Da |
| NCBI Full Name: | peroxisomal acyl-coenzyme A oxidase 3 isoform a |
| NCBI Synonym Full Names: | acyl-CoA oxidase 3, pristanoyl |
| NCBI Official Symbol: | ACOX3 |
| NCBI Protein Information: | peroxisomal acyl-coenzyme A oxidase 3 |
| UniProt Protein Name: | Peroxisomal acyl-coenzyme A oxidase 3 |
| UniProt Synonym Protein Names: | Branched-chain acyl-CoA oxidase; BRCACox; Pristanoyl-CoA oxidase |
| Protein Family: | Peroxisomal acyl-coenzyme A oxidase |
| UniProt Gene Name: | ACOX3 |
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