Anti-ACAA1 Antibody (CAB7422)
- SKU:
- CAB7422
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-ACAA1 Antibody |
| Antibody SKU: | CAB7422 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-300 of human ACAA1 (NP_001598.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | HL-60, MCF7, A-549, Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-300 of human ACAA1 (NP_001598.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LSGA PQAS AADV VVVH GRRT AICR AGRG GFKD TTPD ELLS AVMT AVLK DVNL RPEQ LGDI CVGN VLQP GAGA IMAR IAQF LSDI PETV PLST VNRQ CSSG LQAV ASIA GGIR NGSY DIGM ACGV ESMS LADR GNPG NITS RLME KEKA RDCL IPMG ITSE NVAE RFGI SREK QDTF ALAS QQKA ARAQ SKGC FQAE IVPV TTTV HDDK GTKR SITV TQDE GIRP STTM EGLA KLKP AFKK DGST TAGN SSQV SDGA AAIL LARR SKAE ELGL PI |
| Gene ID: | 30 |
| Uniprot: | P09110 |
| Cellular Location: | Peroxisome |
| Calculated MW: | 34kDa/44kDa |
| Observed MW: | 44kDa |
| Synonyms: | ACAA1, ACAA, PTHIO, THIO |
| Background: | This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | ACAA1: an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Lipid Metabolism - unsaturated fatty acid biosynthesis; Lipid Metabolism - fatty acid; Acetyltransferase; EC 2.3.1.16; Amino Acid Metabolism - valine, leucine and isoleucine degradation Chromosomal Location of Human Ortholog: 3p22.2 Cellular Component: peroxisomal matrix; membrane; intracellular membrane-bound organelle; peroxisome Molecular Function:palmitoyl-CoA oxidase activity; protein binding; acetyl-CoA C-acyltransferase activity Biological Process: fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid beta-oxidation; very-long-chain fatty acid metabolic process; bile acid metabolic process; unsaturated fatty acid metabolic process; cellular lipid metabolic process Disease: D-bifunctional Protein Deficiency |
| NCBI Summary: | This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P09110 |
| NCBI GenInfo Identifier: | 135751 |
| NCBI Gene ID: | 30 |
| NCBI Accession: | P09110.2 |
| UniProt Secondary Accession: | P09110,Q96CA6, G5E935, |
| UniProt Related Accession: | P09110 |
| Molecular Weight: | 424 |
| NCBI Full Name: | 3-ketoacyl-CoA thiolase, peroxisomal |
| NCBI Synonym Full Names: | acetyl-CoA acyltransferase 1 |
| NCBI Official Symbol: | ACAA1 |
| NCBI Official Synonym Symbols: | ACAA; THIO; PTHIO |
| NCBI Protein Information: | 3-ketoacyl-CoA thiolase, peroxisomal; beta-ketothiolase; peroxisomal 3-oxoacyl-CoA thiolase; acetyl-Coenzyme A acyltransferase 1; peroxisomal 3-oxoacyl-Coenzyme A thiolase |
| UniProt Protein Name: | 3-ketoacyl-CoA thiolase, peroxisomal |
| UniProt Synonym Protein Names: | Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase |
| UniProt Gene Name: | ACAA1 |
| UniProt Entry Name: | THIK_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ACAA1 antibody (CAB7422) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using ACAA1 antibody (CAB7422) at dilution of 1:100 (40x lens). |
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